In vitro laxity-testers for knee joints of mice

Abstract

The knee joints of mice can be used as a model for studying the effects of interventions on knee laxity. The goal of this study was to quantify knee joint laxity in vitro. Three devices were developed: a positioning-and cemcnting device, an anterior-posterior (AP) laxity tester and a varus-valgus (VV) laxity tester. The positioningand cementing device was used to position the joint in a reproducible way and to attach clamping pins to the proximal femur and distal tibia using PMMA. The clamping pins were used t…