In vitro DNA binding, molecular docking and antimicrobial studies on a newly synthesized poly(o-toluidine)–titanium dioxide nanocomposite

Morphological, structural, molecular docking and biocidal studies of newly synthesized Ppy‐MA/TiO2 nanocomposites

“…However, in the case of Ppy‐MA/TiO 2 nanocomposites, most of the characteristic peaks of Ppy‐MA and Ppy‐MA/TiO 2 nanocomposites are found to be similar, excepting the characteristic peaks at 1442, 793, 1280, 1194, 1565, and 1475 cm −1 of Ppy‐MA spectrum, which are found to be slightly shifted to a higher wave number and appear at 1477, 796, 1287, 1214, 1569, and 1484 cm −1 in case of Ppy‐MA/TiO 2 nanocomposites. This noticeable change clearly confirms the enhancement of charge delocalization on the polymeric backbone as a consequence of the interfacial interaction with the TiO 2 nanoparticles and Ppy‐MA matrix . Overall, FTIR spectra provide supportive evidence that Ppy‐MA and Ppy‐MA/TiO 2 nanocomposites have been successfully synthesized.…”

“…After nanocomposite formation, the TiO 2 nanoparticles (dark shaded) are found to be entrapped in Ppy‐MA matrix (light shaded), which may be due to the strong interaction between Ppy‐MA and TiO 2 nanoparticles. This justifies the formation of Ppy‐MA/TiO 2 nanocomposites, where TiO 2 nanoparticles appear to act as nanofillers in the Ppy‐MA matrixes . The compositions of different pristine Ppy‐MA and Ppy‐MA/TiO 2 nanocomposites have been analyzed by EDAX (Fig.…”

“…The monomers of Ppy‐MA are thoroughly adsorbed on the surface of TiO 2 nanoparticles. The polymerization is initiated upon the addition of Ammonium persulfate (APS) oxidant, which forms a coating of polymer around the TiO 2 nanoparticles . After nanocomposite formation, the TiO 2 nanoparticles (dark shaded) are found to be entrapped in Ppy‐MA matrix (light shaded), which may be due to the strong interaction between Ppy‐MA and TiO 2 nanoparticles.…”

“…Copolymerization of Ppy‐MA was carried out by chemical oxidative polymerization method . Molar ratios of pyrrole to methyl anthranilate ranged from 1:1 to 10:1 (Table ).…”

“…Copolymerization of Ppy‐MA was carried out as described earlier using chemical oxidative polymerization method . A typical experimental procedure for nanocomposite formation is almost the same until the addition of powdery FeSO 4 ·7H 2 O (139 mg, 0.5 mmol) to the reaction mixture with vigorous stirring (Table ).…”