In vitro digestion and fecal fermentation behaviors of polysaccharides from Ziziphus Jujuba cv. Pozao and its interaction with human gut microbiota

Han, Xue; Zhou, Qian; Gao, Zhe; Lin, Xuan; Zhou, Kaixuan; Cheng, Xinlong; Chitrakar, Bimal; Chen, Hong; Zhao, Wen

doi:10.1016/j.foodres.2022.112022

Cited by 27 publications

(20 citation statements)

References 62 publications

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“…On the other hand, there was a positive correlation between Ruminococcaceae and Enterobacteriaceae and ammonia. Ruminococcaceae and Enterobacteriaceae, as well as Lachnospiraceae and Clostridiaceae, are commensal microorganisms with a significant role in the digestion of amino acids and proteins, thus, justifying their positive correlation with ammonia production [ 131 , 132 , 133 ].…”

Section: Resultsmentioning

confidence: 99%

“…Enterobacteriaceae, in addition to being indicators of intestinal dysbiosis, are also known to cause disease to the host when present in inadequate proportions [ 134 ]. The common cause of disease development is the compromise, erosion of the villi and damage to intestinal cells, leading to inflammatory responses and cytokine release in the intestinal tissue, thus, reducing its potential for nutrient absorption [ 133 ].…”

Section: Resultsmentioning

confidence: 99%

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Functional Fermented Milk with Fruit Pulp Modulates the In Vitro Intestinal Microbiota

Borgonovi

Salgaço

Oliveira

et al. 2022

Foods

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The effect of putative probiotic fermented milk (FM) with buriti pulp (FMB) or passion fruit pulp (FMPF) or without fruit pulp (FMC) on the microbiota of healthy humans was evaluated. FM formulations were administered into a simulator of the human intestinal microbial ecosystem (SHIME®) to evaluate the viability of lactic acid bacteria (LAB), microbiota composition, presence of short-chain fatty acids (SCFA), and ammonium ions. The probiotic LAB viability in FM was affected by the addition of the fruit pulp. Phocaeicola was dominant in the FMPF and FMB samples; Bifidobacterium was related to FM formulations, while Alistipes was associated with FMPF and FMB, and Lactobacillus and Lacticaseibacillus were predominant in FMC. Trabulsiella was the central element in the FMC, while Mediterraneibacter was the central one in the FMPF and FMB networks. The FM formulations increased the acetic acid, and a remarkably high amount of propionic and butyric acids were detected in the FMB treatment. All FM formulations decreased the ammonium ions compared to the control; FMPF samples stood out for having lower amounts of ammonia. The probiotic FM with fruit pulp boosted the beneficial effects on the intestinal microbiota of healthy humans in addition to increasing SCFA in SHIME® and decreasing ammonium ions, which could be related to the presence of bioactive compounds.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Functional Fermented Milk with Fruit Pulp Modulates the In Vitro Intestinal Microbiota

Borgonovi

Salgaço

Oliveira

et al. 2022

Foods

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show abstract

“…The simulated saliva digestion was evaluated using a modified version of the method previously described [ 30 ]. In brief, the simulated saliva was made by dissolving 1.126 g/L of KCl, 1.143 g/L of NaHCO 3 , 0.167 g/L of CaCl 2 , 0.12 g/L of NaCl and 150 U/mL of α-amylase in deionized water, and the pH was adjusted to 7.0 with 0.1 M HCl.…”

Section: Methodsmentioning

confidence: 99%

Simulated Digestion and Fermentation In Vitro by Obese Human Gut Microbiota of Sulforaphane from Broccoli Seeds

Sun

Tang

Hao

et al. 2022

Foods

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Background: sulforaphane is a kind of isothiocyanate, which is obtained by hydrolysis of glucosinolate by the unique myrosinase in plants. It has been proved to prevent the occurrence of many chronic diseases, such as obesity, diabetes and cancer. Objective: The impact of SFN on obese human gut flora, however, has not been established. Methods: In this research, SFN was isolated from broccoli seeds and then refined to achieve 95% purity. Next, an investigation was conducted into the digestion and fermentation processes of SFN. Results: The stability of the SFN in simulated saliva, gastric fluid, and intestinal juice provides evidence that it can reach the gut and be available for utilization by gut microflora. In vitro fermentation of SFN by gut microbes in obese patients results in alteration in constitution of microbiota and production of short chain fatty acids. As the result of SFN ingestion by human gut bacteria, the content of butyric and valeric acids increased 1.21- and 1.46-fold, respectively. In obese human guts, the relative abundances of the beneficial genera including Lactobacillus, Weissella, Leuconosto, Algiphilus and Faecalibacterium significantly increased, whilst the detrimental genera, such as Escherichia-Shigella, Klebsiella, Clostridium_sensu_stricto_1, Sutterella, Megamonas and Proteus drastically declined. Conclusion: Taken together, these findings demonstrate that SFN can be used as a nutraceutical ingredient for obese patients and for improving human health.

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“…When used in combination with ultrasonic waves, DESs have proven to be a powerful and green method for extracting valuable polysaccharides from plant leftovers ( Huang et al, 2017 ; Li, Li, Luo, Ma, & Liu, 2019 ). After extraction, it's important to study how these polysaccharides change during digestion and fermentation because this influences their ability to support good gut health, especially their function as prebiotics that nourish beneficial gut bacteria ( Han et al, 2022 ). Polysaccharides typically resist digestion until reaching the colon, where they support beneficial bacteria and contribute to SCFA production ( Han et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Bioactive properties and gut microbiota modulation by date seed polysaccharides extracted using ultrasound-assisted deep eutectic solvent

Subhash,

Bamigbade,

Tarique

et al. 2024

Food Chemistry: X

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In vitro digestion and fecal fermentation behaviors of polysaccharides from Ziziphus Jujuba cv. Pozao and its interaction with human gut microbiota

Cited by 27 publications

References 62 publications

Functional Fermented Milk with Fruit Pulp Modulates the In Vitro Intestinal Microbiota

Functional Fermented Milk with Fruit Pulp Modulates the In Vitro Intestinal Microbiota

Simulated Digestion and Fermentation In Vitro by Obese Human Gut Microbiota of Sulforaphane from Broccoli Seeds

Bioactive properties and gut microbiota modulation by date seed polysaccharides extracted using ultrasound-assisted deep eutectic solvent

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