In vitro and in vivo assessment of glucose cross‐linked gelatin/zein nanofibrous scaffolds for cranial bone defects regeneration

Deng, Lingli; Li, Yang; Zhang, Hui

doi:10.1002/jbm.b.34498

Cited by 6 publications

(4 citation statements)

References 52 publications

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“…Furthermore, enzymes are costly, limiting their use in large quantities. Surface modification of nano-fiber for multi-point attachment determines undesirable conformational changes of the enzyme in unfriendly environments, which contributes to the durability and stability of the textile-based sensor, such as the crosslinking method, [115,116] the covalent bonding method, [117,118] the adsorption method, [119,120] and the entrapping method. [121,122] Another issue that needs to be solved is that the enzymatic sensor is sensitive to pH, temperature, and time.…”

Section: Metabolite-sensing Devicementioning

confidence: 99%

Electrochemical biosensors and power supplies for wearable health‐managing textile systems

Li,

Jia,

Liang

et al. 2024

Interdisciplinary Materials

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In recent years, wearable electrochemical biosensors have received increasing attention, benefiting from the growing demand for continuous monitoring for personalized medicine and point‐of‐care medical assistance. Incorporating electrochemical biosensing and corresponding power supply into everyday textiles could be a promising strategy for next‐generation non‐invasive and comfort interaction mode with healthcare. This review starts with the manufacturing and structural design of electrochemical biosensing textiles and discusses a series of wearable electrochemical biosensing textiles monitoring various biomarkers (e.g., pH, electrolytes, metabolite, and cytokines) at the molecular level. The fiber‐shaped or textile‐based solar cells and aqueous batteries as corresponding energy harvesting and storage devices are further introduced as a complete power supply for electrochemical biosensing textiles. Finally, we discuss the challenges and prospects relating to sensing textile systems from wearability, durability, washability, sample collection and analysis, and clinical validation.

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Section: Metabolite-sensing Devicementioning

confidence: 99%

Electrochemical biosensors and power supplies for wearable health‐managing textile systems

Li,

Jia,

Liang

et al. 2024

Interdisciplinary Materials

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“…The nanofiber scaffolds presented rapid mineralization in the mimicked body fluid containing bone minerals. The cytotoxic effect on MC3T3e1 cells of the nanofibrous scaffolds was negligible [ 53 ]. When cell growth factors are loaded on the bone-mimicking matrix, there is an improvement in the differentiation and promotion of the proliferation of osteoblasts.…”

Section: Recent Trends In Biomedical Application Of Electrospun Plant...mentioning

confidence: 99%

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application

et al. 2023

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Plant proteins are receiving a lot of attention due to their abundance in nature, customizable properties, biodegradability, biocompatibility, and bioactivity. As a result of global sustainability concerns, the availability of novel plant protein sources is rapidly growing, while the extensively studied ones are derived from byproducts of major agro-industrial crops. Owing to their beneficial properties, a significant effort is being made to investigate plant proteins’ application in biomedicine, such as making fibrous materials for wound healing, controlled drug release, and tissue regeneration. Electrospinning technology is a versatile platform for creating nanofibrous materials fabricated from biopolymers that can be modified and functionalized for various purposes. This review focuses on recent advancements and promising directions for further research of an electrospun plant protein-based system. The article highlights examples of zein, soy, and wheat proteins to illustrate their electrospinning feasibility and biomedical potential. Similar assessments with proteins from less-represented plant sources, such as canola, pea, taro, and amaranth, are also described.

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“…The third is the adsorption method ( Deng et al, 2020 ). The interaction of the enzyme with the fiber’s surface (i.e., ion, van der Waals, and hydrogen bonds) is used to immobilize the enzyme on the nanofiber surface.…”

Section: Electrospun Nanofiber-based Enzymatic and Non-enzymatic Gluc...mentioning

confidence: 99%

Electrospun nanofiber-based glucose sensors for glucose detection

Zhang

Liu

et al. 2022

Front. Chem.

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Diabetes is a chronic, systemic metabolic disease that leads to multiple complications, even death. Meanwhile, the number of people with diabetes worldwide is increasing year by year. Sensors play an important role in the development of biomedical devices. The development of efficient, stable, and inexpensive glucose sensors for the continuous monitoring of blood glucose levels has received widespread attention because they can provide reliable data for diabetes prevention and diagnosis. Electrospun nanofibers are new kinds of functional nanocomposites that show incredible capabilities for high-level biosensing. This article reviews glucose sensors based on electrospun nanofibers. The principles of the glucose sensor, the types of glucose measurement, and the glucose detection methods are briefly discussed. The principle of electrospinning and its applications and advantages in glucose sensors are then introduced. This article provides a comprehensive summary of the applications and advantages of polymers and nanomaterials in electrospun nanofiber-based glucose sensors. The relevant applications and comparisons of enzymatic and non-enzymatic nanofiber-based glucose sensors are discussed in detail. The main advantages and disadvantages of glucose sensors based on electrospun nanofibers are evaluated, and some solutions are proposed. Finally, potential commercial development and improved methods for glucose sensors based on electrospinning nanofibers are discussed.

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In vitro and in vivo assessment of glucose cross‐linked gelatin/zein nanofibrous scaffolds for cranial bone defects regeneration

Cited by 6 publications

References 52 publications

Electrochemical biosensors and power supplies for wearable health‐managing textile systems

Electrochemical biosensors and power supplies for wearable health‐managing textile systems

Agro-Industrial Plant Proteins in Electrospun Materials for Biomedical Application

Electrospun nanofiber-based glucose sensors for glucose detection

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