Biochemical Pharmacology volume 81, issue 8, P976-984 2011 DOI: 10.1016/j.bcp.2011.01.023 View full text
Alfonso Garcia-Bennett, Matthias Nees, Bengt Fadeel

Abstract: Targeted drug therapy or "smart" drug delivery, potentially combined with simultaneous imaging modalities to monitor the delivery of drugs to specific tissues, is arguably the "holy grail" of pharmacology. Therapeutic approaches that exploit nanoparticles to deliver drugs selectively to cancer cells are currently considered one of the most promising avenues in the area of cancer therapeutics and imaging. The potential to deliver active chemotherapeutic drugs in the vicinity or directly within specific tumors v…

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