In reference to <i>Value of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue</i>

Lin, Wen-Dar; Wang, Chen‐Chi; Chen, Sheng‐Hwa

doi:10.1002/lary.28172

Cited by 2 publications

(2 citation statements)

References 4 publications

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“…Fang Q. et al concluded that LLN metastasis was significantly related to lymphovascular invasion, perineural invasion, tumor stage, neck node metastasis, and tumor differentiation with univariate analysis [14]. It was further demonstrated that higher pretreatment NLR was significantly correlated with LLN metastasis, and Lin et al mentioned that high NLR may indicate LLN dissection in patients with early tongue cancer [16]. In this study, however, pretreatment NLR was not significantly different between LLN-positive and LLN-negative patients.…”

Section: Discussionmentioning

confidence: 99%

Lingual Lymph Node Metastases as a Prognostic Factor in Oral Squamous Cell Carcinoma—A Retrospective Multicenter Study

et al. 2021

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Backgrounds and Objectives: The epidemiology and prognostic role of lingual lymph node (LLN) metastasis in patients with oral squamous cell carcinoma (OSCC) remain unclear. Here, we aimed to analyze the clinicopathological features, risk factors, and prognostic role of LLN metastasis in patients with OSCC. Materials and Methods: In total, 945 patients with OSCC were retrospectively analyzed. Clinicopathological features were compared between patients with and without LLN metastasis. The risk factors of LLN metastasis and its effects on survival outcomes were evaluated using multi-variate analysis. Results: LLN metastasis was noted in 67 patients (7.1%). Habitual alcohol consumption and clinical neck node metastasis were independent risk factors for LLN metastasis. LLN metastasis was an independent prognostic factor for disease-free and overall survival, although LLN dissection did not improve survival outcomes. Conclusion: LLN metastasis is an independent adverse prognostic factor. Further prospective studies are needed to fully assess the extent of LLN dissection required in OSCC patients.

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Section: Discussionmentioning

confidence: 99%

Lingual Lymph Node Metastases as a Prognostic Factor in Oral Squamous Cell Carcinoma—A Retrospective Multicenter Study

et al. 2021

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“…Tumors are characterized by three-dimensional growth in multiple directions. However, in previous staging, T stage was mainly calculated based on the maximum diameter of the tumor, and in the mid-1980s, it was noticed that the greater depth of invasion (DOI) suggested a worse prognosis.Melchers LJ [25] and Byers RM [26] suggested that a DOI of 4 mm could be used as a critical value for determining the metastasis of lymph nodes in oral cavity cancer. Li Qun et al found that the cervical lymph node metastasis was as high as 64.29% when the DOI of tongue cancer was >3 mm, while the cervical lymph node metastasis rate was only 5.56% when the DOI was <3 mm.…”

Section: Depth Of Scc Infiltration and Extra-lymph Node Invasionmentioning

confidence: 99%

Progress in the study of lymph node metastasis status of squamous cell carcinoma of the oral and maxillofacial region

2023

AJMHS

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Oral and Maxillofacial squamous cell carcinoma is one of the more common malignant tumors of the maxillofacial region, which develops a high lymph node metastasis rate due to the specificity of the site of occurrence and the richness of the lymphatic traffic network in the neck. Its treatment is mainly based on surgery and radiotherapy and chemotherapy. There are various views on the selection of the extent of lymph node dissection during surgery, and the literature reports that the depth of infiltration of cancer cells has a great influence on lymphatic metastasis, and the AJCC released the latest version of the TNM staging with the addition of the DOI index in the T stage, which has set the direction for the extent of lymphatic dissection. The impact of metastatic lymph node ENE on healing and the psychological pressure and burden of life faced by postoperative patients are also of great concern. In this article, we review the findings of oral and maxillofacial SCC in recent years.

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In reference to Value of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue

Cited by 2 publications

References 4 publications

Lingual Lymph Node Metastases as a Prognostic Factor in Oral Squamous Cell Carcinoma—A Retrospective Multicenter Study

Lingual Lymph Node Metastases as a Prognostic Factor in Oral Squamous Cell Carcinoma—A Retrospective Multicenter Study

Progress in the study of lymph node metastasis status of squamous cell carcinoma of the oral and maxillofacial region

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