Improving patient adherence to secondary prevention medications 6 months after an acute coronary syndrome: observational cohort study

Brieger, David; Chow, Clara K; Gullick, Janice; Hyun, Karice; D’Souza, Mario; Briffa, Tom; Investigators, Concordance

doi:10.1111/imj.13736

Cited by 24 publications

(17 citation statements)

References 24 publications

(21 reference statements)

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“…High indices of adherence to treatment among participants of our investigation can be explained by constant contact with an attending doctor and thorough dynamic monitoring of patients' conditions. Such approach, according to literature data, has significant influence on patients' adherence to treatment [18,19,20].…”

Section: Discussionmentioning

confidence: 99%

Long-Term Consequences of Primary Percutaneous Coronary Intervention in Patients With St-Elevation Myocardial Infarction

et al. 2020

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The aim: To investigate long-term effects of primary percutaneous coronary interventions (pPCI) in patients with STEMI basing on the prevalence of clinically relevant endpoints. Materials and methods: Totally 200 patients with STEMI hospitalized within a period of “therapeutic window” for revascularization were included into the study. 100 patients who additionally to pPCI underwent manual thromboaspiration entered the main group. The comparison group consisted of 100 patients who underwent standard pPCI. Results: Six months after the pPCI, the incidence of either major adverse cardiac events and the combined endpoint did not differ in the main and comparative groups (11.8% vs. 12.5%, p = 0.888 and 18.2% vs. 20.8%, p = 0.658, respectively). There were no significant differences in these endpoints taken separately. In twelve months after procedure, also there were no significant differences between the groups. However, a tendency toward lower incidence of chest pain was observed in the main group (p = 0.08) during this period that was lost in 24 months after pPCI. None of these techniques demonstrated significant advantages during the whole duration of the follow-up period. Conclusions: The addition of manual thromboaspiration to the standard pPCI in patients with STEMI and severe thrombosis of the culprit artery did not significantly influence the prognosis.

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Section: Discussionmentioning

confidence: 99%

Long-Term Consequences of Primary Percutaneous Coronary Intervention in Patients With St-Elevation Myocardial Infarction

et al. 2020

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“…medications, lifestyle, and risk factor control recommendations) [37] and leads to improvements in left ventricular ejection fraction, exercise tolerance, and cardiovascular risk factors [38]. When compared with hospital-based cardiac rehabilitation in a randomized trial, shared-care rehabilitation involving healthcare centers and primary care providers demonstrated similar effects on medication adherence and cardiovascular risk factors [39], as well as similar total healthcare-associated costs [40].…”

Section: Cardiac Rehabilitationmentioning

confidence: 99%

Transition of care to prevent recurrence after acute coronary syndrome: the critical role of the primary care provider and pharmacist

Goldman

Harte²

2020

Postgraduate Medicine

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Despite therapeutic advances, patients with acute coronary syndrome (ACS) are at an increased longterm risk of recurrent cardiovascular events. This risk continues to rise as the number of associated comorbidities, often observed in patients presenting with ACS, increases. Such a level of clinical complexity can lead to gaps in care and subsequently worse outcomes. Guidelines recommend providing an evidence-based post-discharge plan to prevent readmission and recurrent ACS, including cardiac rehabilitation, medication, patient/caregiver education, and ongoing follow-up. A patientcentric multidisciplinary approach is critical for the effective management of the transition of care from acute care in the hospital setting to the outpatient care setting in patients with ACS. Ongoing communication between in-hospital and outpatient healthcare providers ensures that the transition is smooth. Primary care providers and pharmacists have a pivotal role to play in the effective management of transitions of care in patients with ACS. Guideline recommendations regarding the postdischarge care of patients with ACS and the role of the primary care provider and the pharmacist in the management of transitions of care will be reviewed. ARTICLE HISTORY

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“…Secondary prevention has a key role in limiting recurrence; however, patients have difficulty achieving the lifestyle changes required, including increasing levels of physical activity, and medication adherence 3. Data from registries indicate that 6 months post myocardial infarction (MI) only 68% of patients are taking all cardioprotective medications prescribed,4 and <60% are engaging in sufficient exercise 5. When patients do engage in secondary prevention, with the support of effective programmes they can reduce cardiovascular mortality and hospital admission 6 7.…”

Section: Introductionmentioning

confidence: 99%

Design and rationale of the MyHeartMate study: a randomised controlled trial of a game-based app to promote behaviour change in patients with cardiovascular disease

et al. 2019

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IntroductionRecurrence of cardiac events is common after a first event, leading to hospitalisations and increased health burden. Patients have difficulties achieving the lifestyle changes required for secondary prevention and access to secondary prevention programs is limited. This study aims to evaluate the impact of a game-based mobile app, MyHeartMate, which is designed to motivate engagement in secondary prevention behaviours for cardiovascular risk factors.Methods and analysisThe MyHeartMate study is a randomised controlled trial with 6-month follow-up and blinded assessment of the primary outcome. Participants (n=394) with coronary heart disease will be recruited from hospitals in metropolitan Sydney and randomly allocated to standard care or the MyHeartMate app intervention. The intervention group will receive the app, which uses game techniques to promote engagement and lifestyle behaviour change for secondary prevention. The primary outcome is difference between the groups in physical activity (metabolic equivalent of task minutes/week) at 6 months. Secondary outcomes include change in low-density lipoprotein cholesterol, systolic blood pressure, medication adherence, body mass index, waist circumference, mood and dietary changes at 6 months. Data on app engagement, and patient perspectives of usability and acceptability, will also be analysed.Ethics and disseminationThe study has received ethics approval from Northern Sydney Local Health District Human Research Ethics Committee. The study findings will be disseminated via peer-reviewed publications and presentation at international scientific meetings/conferences.Trial registration numberACTRN12617000869370; Pre-results.

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Improving patient adherence to secondary prevention medications 6 months after an acute coronary syndrome: observational cohort study

Cited by 24 publications

References 24 publications

Long-Term Consequences of Primary Percutaneous Coronary Intervention in Patients With St-Elevation Myocardial Infarction

Long-Term Consequences of Primary Percutaneous Coronary Intervention in Patients With St-Elevation Myocardial Infarction

Transition of care to prevent recurrence after acute coronary syndrome: the critical role of the primary care provider and pharmacist

Design and rationale of the MyHeartMate study: a randomised controlled trial of a game-based app to promote behaviour change in patients with cardiovascular disease

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