Biomacromolecules volume 15, issue 1, P350-360 2013 DOI: 10.1021/bm401580k
Ashish Kumar Agrawal, Harshad Harde, Kaushik Thanki, Sanyog Jain
Abstract:

The present study reports the folic acid (FA) functionalized insulin loaded stable liposomes with improved bioavailability following oral administration. Liposomes were stabilized by alternating coating of negatively charged poly(acrylic acid) (PAA) and positively charged poly(allyl amine) hydrochloride (PAH) over liposomes. Furthermore, folic acid was appended as targeting ligand by synthesizing folic acid-poly(allyl amine) hydrochloride conjugate. The insulin entrapped within the freeze-dried formulation…

x
Citation Types
0
29
0
Paper Sections
0
0
0
0
0
Article Types
0
0
0
0