volume 83, issue 6, P1151-1164 2015
DOI: 10.1002/prot.24808
View full text
|
Sign up to set email alerts
|
Share

Abstract: Flexibility and dynamics are important for protein function and a protein’s ability to accommodate amino acid substitutions. However, when computational protein design algorithms search over protein structures, the allowed flexibility is often reduced to a relatively small set of discrete side-chain and backbone conformations. While simplifications in scoring functions and protein flexibility are currently necessary to computationally search the vast protein sequence and conformational space, a rigid represen…

Expand abstract

Search citation statements

Order By: Relevance

Citation Types

0
11
0

Paper Sections

0
0
0
0
0

Publication Types

0
0
0
0

Relationship

0
0

Authors

Journals