Improved bioactivity and composition of Cordyceps militaris cultured with Panax ginseng

Li, Li; Zuo, Jin-Hui; Yi, Fan; Yang, Yun-Li; Yang, Dong; Li, Qinyu; Li, Min-Hui

doi:10.1590/fst.33320

Cited by 3 publications

(4 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Cha and Kim demonstrated that cordycepin can suppress cellular tyrosinase activity and melanin production in cultured B16F0 melanoma cells [61]. Subsequently, Li et al [62] reported that both cordycepin and the mycelia of C. militaris extracted using boiling water can provide tyrosinase-inhibition activity. In our study, the SBRs prepared from C. militaris-which mainly consisted of phenolic compounds, flavonoids, and carbohydrates (as illustrated previously in Table 3)-were also considered as potential alternative sources of anti-tyrosinase-activity-based whitening agents.…”

Section: Tyrosinase Inhibitory Activity Of Crude Sbr Extractsmentioning

confidence: 99%

The Feasibility of Utilizing Cultured Cordyceps militaris Residues in Cosmetics: Biological Activity Assessment of Their Crude Extracts

Pintathong

Chomnunti

Sangthong

et al. 2021

JoF

View full text Add to dashboard Cite

Solid-based residues (SBRs) left from harvesting the fruiting bodies of cultured Cordyceps mushrooms are a challenge to sustainability. Therefore, in this study, the SBRs from the cultivation of Cordyceps militaris (C. militaris) via solid-state fermentation (SSF) were employed to prepare crude extracts, with the aim of considering their possible use in cosmetics. The SBRs obtained from cultivation with solid media containing defatted rice bran mixed with barley, white rice, Riceberry rice, and wheat were named SBR-B, SBR-R, SBR-Rb, and SRB-W, respectively. They were extracted with solvents of differing polarity and then evaluated for their total phenolic content (TPC), total flavonoid content (TFC), and total carbohydrate content (TCC). In addition, antioxidant and tyrosinase inhibitory activities, photoprotection, and cytotoxicity were also assessed. The results revealed that the total bioactive contents and biological capacities of crude SBR extracts were significantly influenced by the types of SBR and extraction solvent (p < 0.05). The SBR-B extracted with hot water exhibited the highest antioxidant activity (66.62 ± 2.10, 212.00 ± 3.43, and 101.62 ± 4.42 mg TEAC/g extract) when assayed by DPPH, ABTS, and FRAP methods, respectively, whereas tyrosinase inhibitory activity (51.13 ± 1.11 mg KAE/g extract) with 90.43 ± 1.96% inhibition at 1 mg/mL was excellently achieved by SBR-Rb extracted by 50% (v/v) ethanol. Correlations between bioactive contents in the crude extracts and their biological activities were mostly proven at a strong level (p < 0.01). The capability of the crude extracts to absorb UV over the range of 290–330 nm disclosed their potential roles as natural UV absorbers and boosters. Cytotoxicity analysis using fibroblast cell lines tested with hot water and 50% (v/v) ethanolic SBR extracts demonstrated safe use within a concentration range of 0.001–10 mg/mL. Interestingly, their fibroblast proliferative capacity, indicating anti-aging properties, was highly promoted. The chemical composition analyzed via LC–MS/MS techniques showed that seven phenolic acids and four flavonoids were identified in the crude SBR extracts. Furthermore, the other compounds present included nucleosides, nucleobases, amino acids, sugars, phospholipids, alkaloids, organic acids, vitamins, and peptides. Therefore, it is emphasized that SBRs from C. militaris can be a prospective source for preparing crude extracts employed in cosmetics. Lastly, they could be further utilized as multifunctional ingredients in cosmetics and cosmeceuticals.

show abstract

Section: Tyrosinase Inhibitory Activity Of Crude Sbr Extractsmentioning

confidence: 99%

The Feasibility of Utilizing Cultured Cordyceps militaris Residues in Cosmetics: Biological Activity Assessment of Their Crude Extracts

Pintathong

Chomnunti

Sangthong

et al. 2021

JoF

View full text Add to dashboard Cite

show abstract

“…7,8 Based on the flower used for scenting, such as jasmine, rose, or osmanthus, the scented tea is named as jasmine tea, rose tea, osmanthus tea, and so forth. 9 Scented tea is a kind of tea infused with certain flowers, which not only has a wonderful aroma, but may also have an exquisite and rich taste. Through the unique scenting process with flowers, the tea could produce various refined flavors.…”

Section: Introductionmentioning

confidence: 99%

“…Flowers are removed after base tea completely absorbs their fragrance, and then the scented tea is completely dried 7,8 . Based on the flower used for scenting, such as jasmine, rose, or osmanthus, the scented tea is named as jasmine tea, rose tea, osmanthus tea, and so forth 9 …”

Section: Introductionmentioning

confidence: 99%

Non‐targeted metabolomic analysis reveals the mechanism of quality formation of citrus flower‐green tea

Yang,

Shen,

et al. 2024

J Sci Food Agric

View full text Add to dashboard Cite

BACKGROUNDCitrus flower‐green tea (CT) is a scented tea processed from green tea (GT) and fresh citrus flower, which is favored by consumers due to its potential health benefits and unique citrus flavor. This study evaluated the quality of CT and revealed the mechanism of its quality formation.RESULTSThe CT had a significant citrus flavor and a good antioxidant activity, and its sensory quality was superior to that of GT. Headspace solid‐phase microextraction‐gas chromatography–mass spectrometry (HS‐SPME‐GC–MS) analysis revealed that the scenting process resulted in a significant increase of alkenes such as β‐pinene, trans‐β‐ocimene, α‐farnesene, isoterpinolene, and γ‐terpinene, as well as a significant decrease of alcohols such as α‐terpineol, L‐menthol, and linalool in CT in comparision with GT. Liquid chromatography‐mass spectrometry/mass spectrometry (LC–MS/MS) analysis revealed that the levels of flavonoids (such as neohesperidin, hesperidin, tangeritin, hesperetin 5‐O‐glucoside, and nobiletin) and alkaloids (such as trigonelline and theobromine) in CT increased significantly after scenting process, while the levels of amino acids (such as valine and L‐phenylalanine) and organic acids (such as ascorbic acid) decreased significantly.CONCLUSIONThese observations showed that the scenting process promoted the absorption of aroma from citrus flowers by GT and the changes in its non‐volatile metabolites, leading to the formation of citrus flavor quality in CT.This article is protected by copyright. All rights reserved.

show abstract

“…It is found that many compounds from plants have good activities in antioxidant, anti-inflammatory, anti-tumor and other aspects (Ha et al, 2022;Khan et al, 2022;Li, et al, 2022;Zhao et al, 2022). Panax ginseng is a traditional medicine used to enhance the immunity, which is therapeutically beneficial in terms of invigorating the Qi, relieving the fatigue, and strengthening the physique (Li et al, 2021). Panax ginseng contains saponins, flavonoids, peptides and other chemical components.…”

Section: Introductionmentioning

confidence: 99%

Extraction of ginsenoside Rg2 from stems-leaves of Panax ginseng and its protective effect on myocardial injury in rats with sepsis

XU,

WANG,

FANG

et al. 2022

Food Sci. Technol

View full text Add to dashboard Cite

Materials and methods Extraction of GRg2 from stems-leaves of Panax ginsengStems-leaves of Panax ginseng were taken, and soaked in water for 1 h, followed by decocting twice, 2 h each time. After filtering for each time, the filtrates were obtained, and combined, followed by concentrating under reduced pressure. The concentrated solution was purified with macroporous resin. The target eluent was collected. After concentrating under reduced

show abstract

Improved bioactivity and composition of Cordyceps militaris cultured with Panax ginseng

Cited by 3 publications

References 7 publications

The Feasibility of Utilizing Cultured Cordyceps militaris Residues in Cosmetics: Biological Activity Assessment of Their Crude Extracts

The Feasibility of Utilizing Cultured Cordyceps militaris Residues in Cosmetics: Biological Activity Assessment of Their Crude Extracts

Non‐targeted metabolomic analysis reveals the mechanism of quality formation of citrus flower‐green tea

Extraction of ginsenoside Rg2 from stems-leaves of Panax ginseng and its protective effect on myocardial injury in rats with sepsis

Contact Info

Product

Resources

About