Archives of Dermatology
 1988
DOI: 10.1001/archderm.124.7.1094
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Improved acanthosis nigricans with lipodystrophic diabetes during dietary fish oil supplementation

E. F. Sherertz1
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Cited by 10 publications

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“…Other therapies found beneficial in various case reports include fish oil, topical triple combination, alexandrite laser, and surgical excision 7,8 . Fish oil in a dosage of 10–20 g per day for 6 months effectively reduced hyperpigmentation and normalized skin texture in one woman with acquired generalized lipodystrophy and AN 7 . Long‐pulsed alexandrite laser treatment led to resolution of AN in one woman 8 …”
Section: Discussionmentioning
confidence: 99%
“…7,8 Fish oil in a dosage of 10-20 g per day for 6 months effectively reduced hyperpigmentation and normalized skin texture in one woman with acquired generalized lipodystrophy and AN. 7 Long-pulsed alexandrite laser treatment led to resolution of AN in one woman. 8 However, all the above treatment modalities have certain limita- Trichloroacetic acid (TCA) is a superficial chemical exfoliating agent which causes coagulation of skin proteins due to its caustic effect.…”
Section: Ta B L E 1 Axillary Grading Of Acanthosis Nigricans 10mentioning
confidence: 96%
“…Oral agents that have shown some efficacy include insulin sensitizers including metformin and thiazolidinediones like rosiglitazone and pioglitazone (in case of insulin resistance), retinoids, dietary fish oils. [4][5][6][7] Long-pulsed alexandrite laser therapy has been reported to improve AN by reducing hyperkeratosis and pigmentation. 8 Chemical peeling with 15% trichloroacetic acid (TCA) has been reported to result in improvement in 6 female patients.…”
Section: Introductionmentioning
confidence: 99%
See 2 more Smart Citations
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Other therapies found beneficial in various case reports include fish oil, topical triple combination, alexandrite laser, and surgical excision 7,8 . Fish oil in a dosage of 10–20 g per day for 6 months effectively reduced hyperpigmentation and normalized skin texture in one woman with acquired generalized lipodystrophy and AN 7 . Long‐pulsed alexandrite laser treatment led to resolution of AN in one woman 8 …”
Section: Discussionmentioning
confidence: 99%
“…7,8 Fish oil in a dosage of 10-20 g per day for 6 months effectively reduced hyperpigmentation and normalized skin texture in one woman with acquired generalized lipodystrophy and AN. 7 Long-pulsed alexandrite laser treatment led to resolution of AN in one woman. 8 However, all the above treatment modalities have certain limita- Trichloroacetic acid (TCA) is a superficial chemical exfoliating agent which causes coagulation of skin proteins due to its caustic effect.…”
Section: Ta B L E 1 Axillary Grading Of Acanthosis Nigricans 10mentioning
confidence: 96%
“…Oral agents that have shown some efficacy include insulin sensitizers including metformin and thiazolidinediones like rosiglitazone and pioglitazone (in case of insulin resistance), retinoids, dietary fish oils. [4][5][6][7] Long-pulsed alexandrite laser therapy has been reported to improve AN by reducing hyperkeratosis and pigmentation. 8 Chemical peeling with 15% trichloroacetic acid (TCA) has been reported to result in improvement in 6 female patients.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“……”
Section: Other Therapiesmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…73 Dietary fish oil treatment has been suggested in patients with lipodystrophic diabetes mellitus and generalized AN, and may result in significant improvement in the AN despite the continuation of niacin treatment. 74 In a study of congenital lipodystrophy, improvement of AN occurred after treatment with recombinant leptin. 47 Treating patients with the HAIR-AN syndrome using oral contraceptives improves cosmesis and reduces hyperpigmentation and androgenic traits by lowering the concentration of free circulating androgens.…”
Section: Differential Diagnosismentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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