Importance of recognizing and preventing blindness from juvenile idiopathic arthritis–associated uveitis

Transition to Adult Rheumatology Care: A Disease-Specific Guide

“…In addition, oligo-JIA patients are at the greatest risk of asymptomatic, chronic anterior uveitis. 17 This risk is highest for antinuclear antibody-positive patients and those who were diagnosed with arthritis before 6 years of age. Chronic anterior uveitis is unique in that it is often silent and can go unrecognized until vision loss is permanent.…”

“…Patients are frequently diagnosed at a young age (median age at onset is <3 years), so they will likely have a longer disease history than other JIA patients. In addition, oligo-JIA patients are at the greatest risk of asymptomatic, chronic anterior uveitis 17 . This risk is highest for antinuclear antibody–positive patients and those who were diagnosed with arthritis before 6 years of age.…”

Response to “Similarities in clinical course and outcome between juvenile idiopathic arthritis (JIA)-associated and ANA-positive idiopathic anterior uveitis: data from a population-based nationwide study in Germany”

“…First, the study used a follow-up interval of 2 years to conclude that antinuclear antibody (ANA)-positive idiopathic uveitis and JIA-associated uveitis (JIA-U) do not significantly differ concerning the clinical course of uveitis, treatment, and response to corticosteroids and disease-modifying anti-rheumatic drugs (DMARDs). Although these pathologies may potentially behave similarly early in the disease course, this conclusion is potentially misleading because the clinical course of JIA-U is often much more chronic and stubborn than idiopathic anterior uveitis [2,3]. Therefore, analysis over a longer period of time is necessary to more clearly elucidate differences in clinical course.…”

Физико-Химические Свойства Крови При ювенильном Идиопатическом Артрите С офтальмопатиями

“…Увеит развивается у 10-20 % от числа больных ЮИА, и такая форма офтальмии считается одной из наиболее частых причин детской слепоты [8,9,[12][13][14]. Установлено [6], что до 9 из 10 больных ЮИА в течение трех лет после дебюта заболевания переносят увеит. Необходимо подчеркнуть, что поражение органа зрения у больных ЮИА может быть первым признаком начинающегося заболевания, еще до суставного его дебюта [10].…”