Implications of between-isolate variation for climate change impact modelling of Haemonchus contortus populations

Vineer, Hannah Rose; Steiner, Jürg; Knapp-Lawitzke, Friederike; Bull, Katie; Fernex, Elke von Son-de; Bosco, Antonio; Hertzberg, Hubertus; Demeler, Janina; Rinaldi, Laura; Morrison, Alison A.; Skuce, Philip; Bartley, David J.; Morgan, Eric R.

doi:10.1016/j.vetpar.2016.10.015

Cited by 13 publications

(12 citation statements)

References 24 publications

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“…However, none have explored the potential for resistance to mitigate climate-driven increases in infection pressure. The simulations presented in this study, under the assumption of equal FEC input, no parasite adaptation to a changing climate (Rose Vineer et al, 2016), and the modest decrease in FECs observed in low EBV compared with high EBV ewes, predicted that pasture infectivity could be reduced to historic levels by introducing resistant ewes.…”

Section: Discussionmentioning

confidence: 91%

Reduced egg shedding in nematode-resistant ewes and projected epidemiological benefits under climate change

Vineer

Baber²,

White³

et al. 2019

International Journal for Parasitology

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Section: Discussionmentioning

confidence: 91%

Reduced egg shedding in nematode-resistant ewes and projected epidemiological benefits under climate change

Vineer

Baber²,

White³

et al. 2019

International Journal for Parasitology

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“…west coast 2 . The impact of these changes on egg maturation and hatching, larval development and subsequent epidemiology of gastro‐intestinal nematode infections is difficult to accurately predict but there have been well‐documented changes in prevalence, seasonality and geographic spread of livestock pathogens in recent years 3–7 …”

Section: Introductionmentioning

confidence: 99%

Integrating applied parasitological and molecular epidemiological methodologies to investigate the capacity of Haemonchus contortus to over‐winter on pasture in Scotland

et al. 2021

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Background: The Barber's Pole worm, Haemonchus contortus is of major concern to sheep producers, particularly in the southern hemisphere. This nematode is also commonly found in many sheep flocks in Northern hemisphere countries but is generally not associated with acute clinical pathology. As with other nematode species, the pattern of disease is changing in the United Kingdom. Changes in management practices, climate, anthelmintic resistance prevalence and parasite adaptation are possible factors thought to be responsible for this. Methods: In the present study, a combination of traditional applied parasitological and molecular species identification techniques were used to assess the capability of H. contortus infective larvae to over‐winter on pasture and infect lambs in early spring. Results: Adult and inhibited H. contortus worms were identified in previously worm‐free tracer lambs that had grazed contaminated pasture in late winter/early spring (February/March). Conclusion: The study illustrated the benefit of using classical applied parasitology techniques in conjunction with molecular species identification methods to explore the epidemiology of gastro‐intestinal nematodes of livestock. This study also demonstrated that larvae were able to survive over‐winter, albeit in small numbers, and potentially contaminate pastures earlier than previously considered in northern regions of the UK.

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“…AHR is difficult to detect in herds because it is caused by an increase in the frequency of resistance alleles through the selection imposed by the repeated use of a given AH (FLEMING et al, 2006). Sheep are hosts to a wide variety of gastrointestinal nematodes that cause clinical symptoms depending on the prevalence of each species, which varies as a function of climate and herd management system (ROSE VINEER et al, 2016). The most prevalent nematodes in most of Brazil are Haemonchus spp., Trichostrongylus spp., Cooperia spp., Oesophagostomum spp.…”

Section: Introductionmentioning

confidence: 99%

Implication of the fecal egg count reduction test (FECRT) in sheep for better use of available drugs

Salgado

Cruz

Rocha

et al. 2019

Rev. Bras. Parasitol. Vet.

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The aim here is to present data on the efficacy of anthelmintics in sheep flocks in Rio de Janeiro, Brazil, and to discuss the interpretation of the fecal egg count reduction test (FECRT) for each nematode genus. Fecal eggs counts and pre- and post-treatment coprocultures were performed, the former to evaluate the efficacy of and the latter to determine the overall parasite prevalence. An additional efficacy test was performed at Farm # 1 a year after the initial test. Severe anthelmintic resistance was found for the flocks, with no FECRT sensitivity at any of the 22 farms evaluated. However, an analysis of the infective larvae showed that some drugs were effective against certain parasitic genera; i.e., levamisole was more effective against Haemonchus spp. and moxidectin against Trichostrongylus spp. In the additional FECRT performed at Farm # 1, moxidectin and nitroxynil were ineffective separately, but when applied in combination they were highly effective due to their efficacy against Haemonchus (nitroxynil) and Trichostrongylus (moxidectin), respectively. The use of the FECRT targeting the parasitic nematode species prevalent on farms may make it possible to choose more effective anthelmintics.

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Implications of between-isolate variation for climate change impact modelling of Haemonchus contortus populations

Abstract: General rightsThis document is made available in accordance with publisher policies. Please cite only the published version using the reference above. Full terms of use are available: http://www.bristol.ac.uk/pure/about/ebr-terms

Cited by 13 publications

References 24 publications

Reduced egg shedding in nematode-resistant ewes and projected epidemiological benefits under climate change

Reduced egg shedding in nematode-resistant ewes and projected epidemiological benefits under climate change

Integrating applied parasitological and molecular epidemiological methodologies to investigate the capacity of Haemonchus contortus to over‐winter on pasture in Scotland

Implication of the fecal egg count reduction test (FECRT) in sheep for better use of available drugs

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