1988
DOI: 10.1055/s-2007-1022979 View full text |Buy / Rent full text
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Abstract: In a preliminary experiment externally reinforced polyurethane prostheses measuring 20 cm in length, with an inner diameter of 3 mm, were implanted in a loop in the femoral artery of six dogs. The dogs received 250 mg acetylsalicylic acid and 25 mg dipyridamol three times a day as anti-thrombocyte aggregation therapy starting three weeks prior to surgery. Anti-thrombocyte aggregation therapy was continued throughout the study. All prostheses remained patent 8, 9, 15 and 17 months after implantation. Patency wa… Show more

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“…A total of 47 articles were considered relevant to the PICO question, including 20 studies suggesting that protocolized aspirin therapy is more effective, or safer than, no aspirin therapy, or other thromboprophylaxis protocols. Twenty‐five studies were considered neutral to the question . The majority of the published literature regarding the administration of aspirin in dogs involves experimental (laboratory) studies (LOE 3) of arterial thrombosis, fewer studies evaluated venous thrombosis .…”
Section: Pico Question: Aspirin Therapymentioning
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“…A total of 47 articles were considered relevant to the PICO question, including 20 studies suggesting that protocolized aspirin therapy is more effective, or safer than, no aspirin therapy, or other thromboprophylaxis protocols. Twenty‐five studies were considered neutral to the question . The majority of the published literature regarding the administration of aspirin in dogs involves experimental (laboratory) studies (LOE 3) of arterial thrombosis, fewer studies evaluated venous thrombosis .…”
Section: Pico Question: Aspirin Therapymentioning
“…The majority of the published literature regarding the administration of aspirin in dogs involves experimental (laboratory) studies (LOE 3) of arterial thrombosis, fewer studies evaluated venous thrombosis . Most were considered of fair quality given that controls were included . Only a few studies used randomized controls, and thus were considered good quality evidence .…”
Section: Pico Question: Aspirin Therapymentioning
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“…In 1978, Annis attempted to develop electrospun polyurethane as a biomaterial for artificial vascular grafts with tetrahydrofuran as a solvent. Since then, more studies have been conducted with the aim of synthesizing pipe tubing material by coiling and adhering a minutely porous electrospinning material to a spinning mandrel with N,N ‐dimethylformamide and neighboring desirable properties with such property‐changing phenomena as elasticity according to the orientation of the electrospun fibers 2–5. Until now, however, research in artificial vascular grafts has not definitely established a materialistic examination of appropriate properties in terms of vascular materials.…”
Section: Introductionmentioning
“…Much effort has been spent on developing compliant vascular prostheses [12][13][14][15][16][17][18][19][20]. These prostheses are mainly produced from polyurethane elastomers, e. g. polyetherurethanes or polyetherurethaneureas of varied thrombogenic activity [21].…”
Section: Introductionmentioning