Implantable microfluidics: methods and applications

Luo, Tao; Zheng, Lican; Chen, Dongyang; Zhang, Chen; Liu, Sirui; Jiang, Chongjie; Xie, Yu; Du, Dan; Zhou, Wei

doi:10.1039/d3an00981e

Cited by 1 publication

(1 citation statement)

References 120 publications

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“…The biocompatible nature of PDMS makes it suitable for applications in biomedical devices. Blending with PS can make the material more robust for various medical applications, such as implantable devices or controlled drug release systems (T. Luo et al, 2023;Arias-Zapata et al, 2016). Patterned PDMS films formed due to isotropic contact instability show a significant influence on selective oil adsorption from oil-water mixtures, making them useful as separation and oil-recovery membranes (Basu and Sarkar, 2019).…”

Section: Introductionmentioning

confidence: 99%

Fabrication of micropatterned thin films through controlled phase separation of polystyrene/polydimethylsiloxane blends by spin coating

Agarwal,

Lu,

Sarkar

2023

Front. Soft Matter

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In this study, we blended two readily available polymers, polydimethylsiloxane (PDMS), a semi-crystalline polymer, and polystyrene (PS), an amorphous polymer, both having widely varying physical properties. The blend is then spin coated to form a thin film. We investigated the effects of relative polymer concentration, spin coating speed, and environmental factors, such as temperature, on the ultimate morphologies of the phase-separated thin films. It was found that it is possible to regulate the morphologies of the thin films to achieve desirable microstructures such as spherical droplets, holes, bi-continuous lamellar structures, and tubules by controlling the fabrication conditions. The polymer blend films with higher PS concentrations were shown to form a bilayer system with an upper PS-rich layer due to the thermodynamic instability of the film caused by the rapid evaporation of solvent, while films with higher PDMS concentrations exhibited cohesive forces that engendered microtubule formation and led to high surface roughness.

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Section: Introductionmentioning

confidence: 99%