(250 words)Purpose Knowledge of different usage patterns emerging during a long-term statin therapy is limited.We aimed at characterizing statin use, including rates of reinitiation after extended periods of non-use, transitions between good and poor adherence, and the effect of the length of a drug-free period on identification of new use. by the end of follow-up. Of those followed-up for 10 years or longer, 51.8% accumulated 6 or more years of treatment with good adherence. In 2007, 27.7% of the initiators having no statin purchases within the previous year had refills during the preceding 10 years.
MethodsConclusion Statin use is dynamic. This should be taken into consideration in clinical practice and when studying the incidence, patterns and health outcomes of statin use.