Impact of mental illness on care for somatic comorbidities in France: a nation-wide hospital-based observational study

Gervaix, Jeanne; Haour, G.; Michel, Morgane; Chevreul, Karine

doi:10.1017/s2045796018000203

Cited by 15 publications

(22 citation statements)

References 56 publications

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“…Characteristics of the 23 included studies are presented in Table 1. Fourteen studies reported health care at end of life (23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36) and 13 studies reported place of death in patients with a serious mental illness (13,28,(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44) and. Four studies reported both outcomes (28,(34)(35)(36).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…There was great variability in the size of the study sample from which the sample of people with serious mental illness. In two studies (28,32), the whole sample comprised eligible adult subjects with serious mental illness, whom were included in the synthesis of results, whilst other studies presented results for subsamples with serious mental illness from a Most studies were from the USA (13,24,(30)(31)(32)34,35,38) and Canada (29,36,43); the remaining studies were from Denmark (41,42), the UK (28,44), France (39), the Netherlands (25), Australia (27,33), New Zealand (23), Japan (40) and Taiwan (26,37). The mean/median age of subjects ranged between 47 and 79.…”

Section: Study Characteristicsmentioning

confidence: 99%

“…The highest proportions of male subjects were 97% and 93% (31,34), however both of these studies used veteran populations. Only three studies had female majorities (36,39,44).…”

Section: Study Characteristicsmentioning

confidence: 99%

“…In the 11 studies that reported place of death, hospital was the most prominent location mentioned in the evidence. This was partly because five studies compared deaths in hospital in-patients with serious mental illness with the general population (13,(37)(38)(39)44). Though these papers explored inhospital mortality, where in-hospital deaths were compared with patients without serious mental illness, these comparative figures were extracted and studies included as descriptors of place of death.…”

Section: Hospital Deathsmentioning

confidence: 99%

“…In order not to exclude some relevant studies, we took an inclusive approach and there is variation amongst the populations included in this review. Some samples (35,39,43) included patients who had a psychiatric admission, contact or prescription, although these may have not been a diagnosis we initially intended to limit the review to, they were serious enough to warrant inpatient care, thus were included as they were considered serious mental illness. We restricted our search strategy to middle and high income countries to avoid making comparisons between countries with different economic resources and priorities.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

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End-of-life care and place of death in adults with serious mental illness: A systematic review and narrative synthesis

et al. 2019

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Background: People with serious mental illness have greater mortality risk than the general population. They experience health care inequalities throughout life; it is not clear if this persists to end of life. Aim: Assess the empirical evidence describing end-of-life care and place of death for people with serious mental illness. Design: A systematic review of original, peer-reviewed research, following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data were analysed using a narrative synthesis approach. Data sources: Five online databases (Embase, PsycArticles, PsycINFO, Medline, PubMed) and additional sources were searched (without time restriction) for primary research reporting health care utilisation in the last year of life or place of death in adults with serious mental illness. Results: After full-text screening, 23 studies were included. We found studies reporting hospital admissions, emergency department care, palliative care, and general practitioner (GP) visits at end of life. We found conflicting evidence for the association between serious mental illness and end-of-life care, although different patient groups, settings and measures were used across studies. People with serious mental illness were more likely to die in care homes than the general population. There were no patterns for other places of death. Conclusions: The evidence was sparse and heterogeneous, demonstrating variability in patterns and reporting of health care use and with little consensus on where people with serious mental illness are likely to die. Given that people with serious mental illness have increased mortality risk, this gap in the knowledge around end-of-life care outcomes is concerning; this area of research needs further development.

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Section: Study Characteristicsmentioning

confidence: 99%

Section: Study Characteristicsmentioning

confidence: 99%

“…The highest proportions of male subjects were 97% and 93% (31,34), however both of these studies used veteran populations. Only three studies had female majorities (36,39,44).…”

Section: Study Characteristicsmentioning

confidence: 99%

Section: Hospital Deathsmentioning

confidence: 99%

Section: Strengths and Limitationsmentioning

confidence: 99%

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End-of-life care and place of death in adults with serious mental illness: A systematic review and narrative synthesis

et al. 2019

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Association Between Mental Health Disorders and Mortality Among Patients With COVID-19 in 7 Countries

et al. 2021

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IMPORTANCE Heterogeneous evidence exists for the association between COVID-19 and the clinical outcomes of patients with mental health disorders. It remains unknown whether patients with COVID-19 and mental health disorders are at increased risk of mortality and should thus be targeted as a high-risk population for severe forms of COVID-19.OBJECTIVE To determine whether patients with mental health disorders were at increased risk of COVID-19 mortality compared with patients without mental health disorders.DATA SOURCES For this systematic review and meta-analysis, MEDLINE, Web of Science, and Google Scholar were searched from inception to February 12, 2021. Bibliographies were also searched, and the corresponding authors were directly contacted. The search paradigm was based on the following combination: (mental, major[MeSH terms]) AND (COVID-19 mortality[MeSH terms]). To ensure exhaustivity, the term mental was replaced by psychiatric, schizophrenia, psychotic, bipolar disorder, mood disorders, major depressive disorder, anxiety disorder, personality disorder, eating disorder, alcohol abuse, alcohol misuse, substance abuse, and substance misuse.STUDY SELECTION Eligible studies were population-based cohort studies of all patients with identified COVID-19 exploring the association between mental health disorders and mortality.DATA EXTRACTION AND SYNTHESIS Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) reporting guideline was used for abstracting data and assessing data quality and validity. This systematic review is registered with PROSPERO. MAIN OUTCOMES AND MEASURESPooled crude and adjusted odds ratios (ORs) for the association of mental health disorders with mortality were calculated using a 3-level random-effects (study/country) approach with a hierarchical structure to assess effect size dependency.RESULTS In total, 16 population-based cohort studies (data from medico-administrative health or electronic/medical records databases) across 7 countries (1 from Denmark, 2 from France, 1 from Israel, 3 from South Korea, 1 from Spain, 1 from the UK, and 7 from the US) and 19 086 patients with mental health disorders were included. The studies covered December 2019 to July 2020, were of good quality, and no publication bias was identified. COVID-19 mortality was associated with an increased risk among patients with mental health disorders compared with patients without mental health disorders according to both pooled crude OR (1.75 [95% CI, 1.40-2.20]; P<.05) and adjusted OR (1.38 [95% CI, 1.15-1.65]; P<.05). The patients with severe mental health disorders had the highest ORs for risk of mortality (crude OR: 2.26 [95% CI, 1.18-4.31]; adjusted OR: 1.67 [95% CI, 1.02-2.73]). CONCLUSIONS AND RELEVANCEIn this systematic review and meta-analysis of 16 observational studies in 7 countries, mental health disorders were associated with increased COVID-19-related mortality. Thus, patients with mental health disorders should have been targeted as a high-risk population for severe forms of COVID-19,...

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Risk factors for poor COVID-19 outcomes in patients with psychiatric disorders

Cheng,

Shih,

et al. 2023

Brain, Behavior, and Immunity

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Impact of mental illness on care for somatic comorbidities in France: a nation-wide hospital-based observational study

Abstract: Inadequate primary care of mentally ill patients leads to more serious conditions upon admission to hospital and avoidable hospitalisations. It is, therefore, necessary to improve primary care and prevention for those patients.

Cited by 15 publications

References 56 publications

End-of-life care and place of death in adults with serious mental illness: A systematic review and narrative synthesis

End-of-life care and place of death in adults with serious mental illness: A systematic review and narrative synthesis

Association Between Mental Health Disorders and Mortality Among Patients With COVID-19 in 7 Countries

Risk factors for poor COVID-19 outcomes in patients with psychiatric disorders

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