2020
DOI: 10.1590/0102-672020200003e1524
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Abstract: Background: KRAS mutations are important events in colorectal carcinogenesis, as well as negative predictors of response to EGFR inhibitors treatment. Aim: To investigate the association of clinical-pathological features with KRAS mutations in colorectal cancer patients treated. Methods: Data from 69 patients with colorectal cancer either metastatic at diagnosis or later, were retrospectively analyzed. The direct sequencing and pyrosequencing techniques were related to KRAS exon 2. The mutation diagnosis and… Show more

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Cited by 2 publications
(40 citation statements)
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“…Other randomized trials validated CS in specimens with gastric cancer 5 . LN retrieval is troublesome in rectal cancer following chemoradiation therapy, and in gastric cancer, the required number of LNs for adequate staging is high 16 .…”
Section: Introductionmentioning
confidence: 99%