Impact of BMI on Adverse Events After Laparoscopic and Open Surgery for Rectal Cancer

Hirpara, Dhruvin H.; O’Rourke, Colin; Azin, Arash; Quereshy, Fayez A.; Wexner, Steven D.; Chadi, Sami A.

doi:10.1007/s12029-021-00612-2

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…Although a recent meta-analysis indicated that laparoscopy is not inferior to laparotomy [23], considering the cost-effectiveness [24], variables such as higher BMI [25], patients' [32], or EuroQol-5D [EQ-5D] [33] instruments) was an important long-term outcome (particularly in older adults). However, to our knowledge, there are few studies regarding postoperative QOL [34,35].…”

Section: Discussionmentioning

confidence: 99%

Longitudinal analysis of long-term outcomes of colorectal cancer after laparotomy and laparoscopic surgery: The Shizuoka study

Kojimahara,

Sato,

Sato

et al. 2023

PLoS ONE

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Background Long-term cancer prognosis after initial surgical procedures is an unlikely endpoint for clinical trials. Medical claim databases may aid in addressing this issue regardless of limited information on disease and patient background. However, the long-term prognosis (especially regarding long-term care needs) following surgical procedures remains unclear. This study aimed to assess whether long-term outcomes, such as the exacerbation of long-term care needs and mortality, differ with surgical methods. Methods Using a longitudinal study with linkage between medical claim and long-term care database, patients with primary colorectal cancer who underwent initial colonoscopies were identified through anonymized data in Japan (Shizuoka Kokuho Database, 2012–2018). Odds ratios (ORs) for long-term outcomes (long-term care needs and all-cause mortality during a 6.5-year follow-up period) were analyzed using logistic regression to compare laparoscopy and endoscopic surgery to laparotomy. Results Overall, 3,744 primary colorectal cancer cases (822 laparotomies, 705 laparoscopies, and 2,217 endoscopic surgeries) were included. Compared to the laparotomy group, the crude OR for exacerbation of long-term care needs in the laparoscopic surgery group was 0.376 (95% confidence interval, 0.227, 0.624), while the OR for all-cause mortality was 0.22 (0.329, 0.532). Conclusion This is the first study to analyze long-term prognosis after surgery for patients with colorectal cancer to combine medical and long-term needs data. As the national health insurance claim database rarely includes information on cancer stage and comorbidities, better prognosis on endoscopic surgery may need careful interpretation. Therefore, laparoscopy has superior outcomes in terms of long-term care needs and mortality compared to those of laparotomy.

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Section: Discussionmentioning

confidence: 99%

Longitudinal analysis of long-term outcomes of colorectal cancer after laparotomy and laparoscopic surgery: The Shizuoka study

Kojimahara,

Sato,

Sato

et al. 2023

PLoS ONE

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“…5,6 Several studies found that obesity was associated with higher rates of anastomotic leakage, infections, myocardial infarction, deep vein thrombosis and postoperative sexual dysfunction or dysuria, and increased the possibility of conversion. [7][8][9] Besides, a meta-analysis proved that visceral obesity increased the surgical difficulty and morbidity. 10 We perform approximately six hundreds of LRCS annually.…”

Section: Introductionmentioning

confidence: 99%

A Space Expander of Laparoscopic Rectal Cancer Surgery for Overweight or Obese Patients

Chen

Zhu

et al. 2023

Surg Innov

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Background/Need Laparoscopic rectal cancer surgery (LRCS) has become a preferred approach for its minimal invasion and fast postoperative recovery. But it is challenging for the tumors of the middle and lower rectum, especially for overweight or obese patients. Methodology We present a space expander of laparoscopic rectal cancer surgery, which is a simple tool to widen the perirectal space, as to facilitate the procedure of total mesorectal excision (TME) during the rectal cancer surgery. It has several advantages of lower demand for an assistant, less risk of surgical complications and good feasibility. Device Description It is designed as a cylindrical shape, and it is the first invented device to help surgeons safely perform accurate TME on overweight or obese patients during LRCS. With this method, we are able to dissect the rectal wall circumferentially in a safe and quick way. Preliminary Results Our previous pig experiments indicated that the learning curve for this technique was as short as 10 minutes. Current status Further clinical trials will be conducted on its efficacy and safety in the future.

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Effects of different weight loss programmes on oncological outcomes following curative resection of digestive tract cancers

Niaz

Seabrook

Niaz

et al. 2022

Cochrane Database of Systematic Reviews

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Impact of BMI on Adverse Events After Laparoscopic and Open Surgery for Rectal Cancer

Cited by 6 publications

References 24 publications

Longitudinal analysis of long-term outcomes of colorectal cancer after laparotomy and laparoscopic surgery: The Shizuoka study

Longitudinal analysis of long-term outcomes of colorectal cancer after laparotomy and laparoscopic surgery: The Shizuoka study

A Space Expander of Laparoscopic Rectal Cancer Surgery for Overweight or Obese Patients

Effects of different weight loss programmes on oncological outcomes following curative resection of digestive tract cancers

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