2015
DOI: 10.1016/j.jval.2015.03.1513
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Abstract: OBJECTIVES: The aims of this study were (1) to determine the change in patients' knowledge about their disease and treatment; (2) to assess the percent change in values of glycated hemoglobin (HbA1c) and change in blood pressure in mmHg; and (3) to evaluate adherence status, measured through pill counts. METHODS: A prospective study was conducted using patients with a diagnosis of both T2DM and hypertension at Arauco hospital in Arauco, Chile. Each patient participated in three interviews over a period of six … Show more

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Cited by 8 publications
(13 citation statements)
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“…Previous research assessing the impact of medication synchronization programs has not included HIV-infected patients and evaluated medication classes other than ART. 9,10,16 The results of the present investigation align with those of previous studies associating medication synchronization and improved PDC in drug classes for other chronic disease states. The results of the univariate analysis in this investigation found even greater odds of adherence to ART in patients with HIV/AIDS enrolled in medication synchronization compared with other chronic disease states that have been studied: 10.67 times compared with 6.1 times.…”
Section: Discussionsupporting
confidence: 89%
“…Previous research assessing the impact of medication synchronization programs has not included HIV-infected patients and evaluated medication classes other than ART. 9,10,16 The results of the present investigation align with those of previous studies associating medication synchronization and improved PDC in drug classes for other chronic disease states. The results of the univariate analysis in this investigation found even greater odds of adherence to ART in patients with HIV/AIDS enrolled in medication synchronization compared with other chronic disease states that have been studied: 10.67 times compared with 6.1 times.…”
Section: Discussionsupporting
confidence: 89%
“…A few studies outside oncology have examined whether improving synchronization can improve adherence. Two studies in regional pharmacy chains 37,38 recently showed that patients who enrolled in a refill synchronization program improved their odds of adherence by more than 3 times in comparison with controls who did not choose to enroll. A synchronization study at a national chain that used a stronger wait-list design found smaller effects (a 7.5% improvement in adherence in the intervention group vs a 4.7% improvement in the waitlist group), 39 and this suggests that further research is needed.…”
Section: Discussionmentioning
confidence: 99%
“…Given the observational study design, we could not account for all variables that might affect the relationship between synchronization and adherence or the possibility that those who are more likely to adhere are also more likely to arrange more synchronized prescription fills. However, the evidence from cohort studies 37,38 and one controlled trial 39 outside cancer suggest that synchronizing medications is likely to be an effective intervention. There are few reported descriptions of synchronization estimates in the literature, so we were unable to compare the findings for our cohort with those for other cohorts; future studies should examine the range of synchronization across cohorts.…”
Section: Discussionmentioning
confidence: 99%
“…While this feasibility study was not designed to statistically assess the effectiveness of the intervention to improve clinical measures like HbA1c and PDC, some patients in the sample did appear to experience positive changes. Medication synchronization has been linked to patients refilling their prescriptions more regularly [31,40], although the link to clinical outcomes has yet to be established. Studies of pharmacist-led diabetes interventions are mixed, particularly with their ability to decrease HbA1c through interventions focused on education and self-care counseling [27,41].…”
Section: Discussionmentioning
confidence: 99%