“…Studies indicate that accurate interpretation of optical biopsies follows a learning curve, and this learning curve can be achieved rapidly in both academic and community practice settings. [54][55][56][57][58][59] This ASGE Technology Committee systematic review and meta-analysis therefore confirms that the thresholds established by the ASGE PIVI for the real-time endoscopic assessment of the histology of diminutive polyps have been met, at least for NBI, with endoscopists who are experts in using these advanced imaging technologies and when assessments are made with high confidence. The ASGE Technology Committee therefore endorses the use of NBI for both the "diagnose-and-leave" strategy for diminutive rectosigmoid hyperplastic polyps and the "resect-and-discard" strategy for diminutive adenomatous polyps by endoscopists trained in using this technology for polyp characterization, making assessments with high confidence.…”