Immunostimulatory and antioxidant activities of a lignin isolated from Conocarpus erectus leaves

Santos, Dayane Kelly Dias do Nascimento; Barros, Bárbara Rafaela da Silva; Aguiar, Lethícia Maria de Souza; Filho, Iranildo José da Cruz; Lorena, Virgínia Maria Barros de; Melo, Cristiane Moutinho Lagos de; Napoleão, Thiago Henrique

doi:10.1016/j.ijbiomac.2020.02.052

Cited by 25 publications

(13 citation statements)

References 60 publications

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“…This plant is generally cultivated for ornamental and landscaping purpose in municipal area. However, biomass waste disposal issue may occur from this plant due to improper conduct [ 8 , 9 ]. The Conocarpus trunk part fibre contains great amount lignocellulosic components and its structural built-up is closely similar to the reported study on Ficus natalensis plant [ 10 ], which serve as major cellulose source.…”

Section: Introductionmentioning

confidence: 99%

Isolation and Production of Nanocrystalline Cellulose from Conocarpus Fiber

et al. 2021

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Conocarpus fiber is a lignocellulosic biomass rich in cellulose potentially used for producing nanocrystalline cellulose (NCC), a biomaterial extensively employed in various application fields. In the present work, different hydrolysis times of 10, 20 and 30 min were applied to chemically pre-treated Conocarpus fiber to produce CPNC1, CPNC2, and CPNC3 particles. With acid hydrolysis treatment, the yield of NCC product was successfully retained at 17–19%. Individual, rod-like shapes of NCC particles could be clearly observed under microscopy examination. From chemical composition analysis, a relatively pure cellulose compartment was produced for all NCC samples with substantial removal of lignin and hemicellulose. The physicochemical analysis proved that each nanoparticle sample possessed strong cellulose crystalline structure. For thermal analyses, the heat resistance of NCCs was gradually enhanced with the increased hydrolysis times. Therefore, the extracted NCC product from Conocarpus fiber could be a green nano-filler for developing nanocomposite material in the future.

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Section: Introductionmentioning

confidence: 99%

Isolation and Production of Nanocrystalline Cellulose from Conocarpus Fiber

et al. 2021

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“…Several studies reported correlation between phenolic OH content and antioxidant performance of lignin due to radical scavenging ability of phenolic as hydrogen donor groups (Ugartondo et al, 2008;Vanderghem et al, 2011). Furthermore, pretreatment of lignin to increase its phenolic hydroxyl content for antioxidant property enhancement via homogenous acid approach (e.g., diluted H 2 SO 4 , HCl, and H 3 PO 4 ) has been reported (do Nascimento Santos et al, 2020;Lourençon et al, 2021). The phenolic-OH content of lignin was increased from 69.7 to 303.6 mg/g when diluted H 2 SO 4 pretreatment was applied which led to antioxidant capacity enhancement (IC 50 decreased from 173.4 to 38.5 μg/mL) (You et al, 2022).…”

Section: Uv Absorption and Antioxidant Performance Of The Extracted A...mentioning

confidence: 99%

Effects of thermal and physical modification on functional properties of organosolv lignin from sugarcane bagasse and its application in cosmeceutical products

et al. 2023

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Organosolv lignin is an emerging bio-additive for creating functional properties in various products with its advantages in high-purity, sulfur-free, biocompatibility, and solubility in green solvents. In this study, effects of thermal and physical modification on alterations of functional properties and particle size distribution of isolated organosolv lignin from sugarcane bagasse (OLB) were studied. Thermal treatment of OLB at increasing temperatures from 170 to 230°C in 70%w/w aqueous ethanol led to alteration of phenolic hydroxyl content, while ultrasonication resulted in homogeneous size distribution of the modified OLB according to laser diffraction and scanning electron micrograph. The highest ultraviolet light absorbance and antioxidant activities were obtained at 190°C treatment which were correlated to the highest phenolic group content. Application of the modified OLB at 3% w/w in a base cream formulation resulted in enhancement of the anti-UV activity to exceed SPF 50 with increasing antioxidant activity in the product. The work provides basis on modification of organosolv lignin for application as a potent functional additive in cosmeceutical products.

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“…Another natural biomaterial, lignin was also explored by researchers for its antioxidant property [ 164 , 165 , 166 , 167 , 168 ]. It is a type of organic polymer present in the tissues of most plants.…”

Section: Bioengineering Approaches To Regenerating Cns and Pnsmentioning

confidence: 99%

Antioxidant for Neurological Diseases and Neurotrauma and Bioengineering Approaches

2021

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Antioxidants are a class of molecules with an innate affinity to neutralize reactive oxygen species (ROS), which are known to cause oxidative stress. Oxidative stress has been associated with a wide range of diseases mediated by physiological damage to the cells. ROS play both beneficial and detrimental roles in human physiology depending on their overall concentration. ROS are an inevitable byproduct of the normal functioning of cells, which are produced as a result of the mitochondrial respiration process. Since the establishment of the detrimental effect of oxidative stress in neurological disorders and neurotrauma, there has been growing interest in exploring antioxidants to rescue remaining or surviving cells and reverse the neurological damage. In this review, we present the survey of different antioxidants studied in neurological applications including neurotrauma. We also delve into bioengineering approaches developed to deliver antioxidants to improve their cellular uptake in neurological applications.

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Immunostimulatory and antioxidant activities of a lignin isolated from Conocarpus erectus leaves

Cited by 25 publications

References 60 publications

Isolation and Production of Nanocrystalline Cellulose from Conocarpus Fiber

Isolation and Production of Nanocrystalline Cellulose from Conocarpus Fiber

Effects of thermal and physical modification on functional properties of organosolv lignin from sugarcane bagasse and its application in cosmeceutical products

Antioxidant for Neurological Diseases and Neurotrauma and Bioengineering Approaches

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