Immunohistologic patterns of congenital nevocellular nevi

On the Development of Neurocutaneous Units—Implications for the Histogenesis of Congenital, Acquired, and Dysplastic Nevi

“…38,39 This strongly suggests that giant CMN begin beneath the epidermis and is consistent with the nerve sheath origin of giant CMN. Using giant CMN as a starting point leads to a view of nevogenesis very different from Unna's.…”

“…After birth, some CMN grow more than others. 38,39,46 Any theory of nevogenesis must attempt a cogent scientific explanation for a wide variety of distinctive features of prenatal and postnatal nevi. The MDP/NCU model explains these features in terms of neurocutaneous development.…”

Results of early curettage of giant congenital melanocytic nevi; a report of eight cases and review of the literature

“…Re-pigmentation first appeared 2 months after curettage, with a mean of 3 months. Patients [15,21,22]. Others noticed the importance of nevus size in determining the extent of dermal involvement already in the early postnatal period [1,8,24].…”

Age- and Site-Specific Variation in the Dermoscopic Patterns of Congenital Melanocytic Nevi

“…The histologic appearance of the findings from the repeated biopsies revealed no noteworthy change compared with the ap- pearance of the original biopsy findings. 26 This suggests that major events in the evolution of CMN do not occur in the first and second decades of life but does not exclude the possibility that those events may occur later in life.…”