1992
DOI: 10.1001/archderm.128.2.214
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Immunofluorescence abnormalities in lichen planopilaris

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Cited by 9 publications
(13 citation statements)
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“…In direct immunofluorescence studies in lichen planopilaris of the scalp, linear deposition of immunoglobulin was found restricted to the BMZ of the hair follicle, without involvement of the adjacent epidermis and without deposits of fibrin. 11 If the activity of enoxaparin in LP were primarily anticoagulant, this might be in accordance with the unsatisfactory response of scalp involvement in our patients. However, it seems reasonable to consider that the small doses of enoxaparin administered were devoid of anticoagulant activity.…”
Section: Discussionsupporting
confidence: 81%
“…In direct immunofluorescence studies in lichen planopilaris of the scalp, linear deposition of immunoglobulin was found restricted to the BMZ of the hair follicle, without involvement of the adjacent epidermis and without deposits of fibrin. 11 If the activity of enoxaparin in LP were primarily anticoagulant, this might be in accordance with the unsatisfactory response of scalp involvement in our patients. However, it seems reasonable to consider that the small doses of enoxaparin administered were devoid of anticoagulant activity.…”
Section: Discussionsupporting
confidence: 81%
“…The condition usually tends to resolve spontaneously, leaving atrophic scars on the scalp. 4,5 The trichogram in LPP shows anagen hair surrounded by thickened sheets. In the initial phases, when inflammatory lesions are present, differential diagnosis is with seborrheic dermatitis or DLE.…”
Section: Discussionmentioning
confidence: 99%
“…In addition to the granular deposits of Ig and complement at the DEJ, the same deposits are sometimes observed around the superficial blood vessels in DLE lesional skin (10–20% of cases) 22,23 , 25,26 , 30 . As regards LPP, Joannides and Bystryn 37 demonstrated with DIF IgA and IgG linear deposits restricted to the basement membrane of hair follicles and not involving the DEJ of the overlying epidermis. Junctional deposits of fibrin were present in only 1 out of 7 patients studied and were linear in appearance.…”
Section: Discussionmentioning
confidence: 97%
“…38 Therefore, in the current study, ®brillar deposits of ®brin at DEJ seldom associated with IgM or C 3 granular deposits were considered suggestive for LPP. 31,32,37 As regards localized SCL, speci®c immunopathologic ®ndings are lacking. Only in 10±20% of cases IgM or IgG microgranular deposits are detectable at the DEJ.…”
Section: Discussionmentioning
confidence: 99%
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