Archives of Dermatology
 1991
DOI: 10.1001/archderm.127.6.843
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Immunoblot assay as an aid to the diagnoses of unclassified cases of pemphigus

T. Hashimoto1
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Cited by 18 publications

(13 citation statements)
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“…A few cases have been reported in the literature. Earlier cases were confirmed by histology and immunoblotting [1,2,3,4,5,6] while the transition in more recent cases has been demonstrated by a change in desmoglein (Dsg) 1 and 3 autoantibody profile by Dsg ELISA testing [6,7,8,9,10,11]. We report 3 cases that showed transition from PV to PF confirmed by Dsg ELISA.…”
Section: Introductionmentioning
confidence: 78%
“…In the literature, there are at least 16 reported cases of transition of PV to PF [1,2,3,4,5,6,7,8,9,10,11] including one that reverted to PV again [7] (table 1). In contrast, there are only 3 reported cases of transition from PF to PV [1, 6, 7] and 3 cases of PV-PF overlap [4, 6].…”
Section: Discussionmentioning
confidence: 99%
“…In contrast, there are only 3 reported cases of transition from PF to PV [1, 6, 7] and 3 cases of PV-PF overlap [4, 6]. The period of transition from PV to PF ranged from 6 months to 20 years with a median of 3 years.…”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…A few cases have been reported in the literature. Earlier cases were confirmed by histology and immunoblotting [1,2,3,4,5,6] while the transition in more recent cases has been demonstrated by a change in desmoglein (Dsg) 1 and 3 autoantibody profile by Dsg ELISA testing [6,7,8,9,10,11]. We report 3 cases that showed transition from PV to PF confirmed by Dsg ELISA.…”
Section: Introductionmentioning
confidence: 78%
“…In the literature, there are at least 16 reported cases of transition of PV to PF [1,2,3,4,5,6,7,8,9,10,11] including one that reverted to PV again [7] (table 1). In contrast, there are only 3 reported cases of transition from PF to PV [1, 6, 7] and 3 cases of PV-PF overlap [4, 6].…”
Section: Discussionmentioning
confidence: 99%
“…In contrast, there are only 3 reported cases of transition from PF to PV [1, 6, 7] and 3 cases of PV-PF overlap [4, 6]. The period of transition from PV to PF ranged from 6 months to 20 years with a median of 3 years.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…However, this does not negate the fact that the WB method reveals the majority of pemphigus antigen determinants. Indeed, a couple of studies 31,32 have found a good correlation between IIF titres and immunoblotting reactivity.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Immunoblotting and enzyme-linked immunosorbent assay (ELISA) have been used to demonstate the autoantibodies in pemphigus 1-10. Unlike ELISA, immunoblotting does not yield a quantitative result, and it may produce false negative results 10.…”
Section: Discussionmentioning
confidence: 99%
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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