Immune Thrombocytopenic Purpura, a rare manifestation of active tuberculosis: Case report

Abstract

Although a large number of hematological disorders related to tuberculosis have been described, anemia, leukocytosis, and pancytopenia are the most frequent. Thrombocytopenia is a rare manifestation of active tuberculosis. We present the case of a 38-year-old man who presented with subacute respiratory symptoms and a platelet count of 5000 per microliter in the context of active tuberculosis, where no other causes for thrombocytopenia were found. Tuberculosis (TB) is currently considered a public health issue worldwide and one of the leading causes of morbidity and mortality in Latin America and Colombia. 1 Thrombocytopenia is a hematological disorder characterized by a platelet count lower than 100,000 per microliter (mcl) and is considered severe with values below 20 000 per mcl. Immune thrombocytopenic purpura (ITP) is a cause of thrombocytopenia that occurs due to antibody-mediated platelet destruction. It can be primary, or secondary to autoimmune, malignant, or infectious diseases such as

Immune Thrombocytopenic Purpura Secondary to Peritoneal Tuberculosis Patient with Anti-Tuberculosis Drug-Induced Liver Injury. A Case Report

“…ITP is an autoimmune disease characterized by thrombocytopenia as the only haematological manifestation. The two main diagnostic criteria for ITP are thrombocytopenia in the context of a normal blood count, a normal smear, and the exclusion of primary conditions capable of causing thrombocytopenia (7). ITP is further differentiated into primary ITP or secondary ITP (6).…”