Imaging of Eosinophilic Lung Diseases

Price, Max; Gilman, Matthew D.; Carter, Brett W.; Sabloff, Bradley S.; Truong, Mylene T.; Wu, Carol C.

doi:10.1016/j.rcl.2016.05.008

Cited by 33 publications

(24 citation statements)

References 92 publications

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“…A typical radiologic feature of AEP is the localization in the upper lobes without basilar involvement of unilateral or bilateral opacities, typically with no segmental distribution. 11 …”

Section: Discussionmentioning

confidence: 99%

<p>May 2020: Is It Always COVID-19 No Matter What?</p>

Livrieri¹,

Ghidoni²,

Piro³

et al. 2020

IMCRJ

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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing a massive outbreak throughout the world. In this period, diseases other than coronavirus disease (COVID-19) have not disappeared; however, it is hard for doctors to diagnose diseases that can mimic the clinical, radiological, and laboratory features of COVID-19, especially rare lung diseases such as acute eosinophilic pneumonia (AEP). We report the clinical case of a young patient who presented to the Emergency Department with respiratory failure and clinical symptoms, radiological aspects, and blood tests compatible with COVID-19; two swabs and a serology test for SARS-CoV-2 were performed, both resulted negative, but the respiratory failure worsened. Peripheral eosinophilia guided us to consider the possibility of a rare disease such as AEP, even if radiology findings were not pathognomonic. Therefore, we decided to perform a flexible bronchoscopy with bronchoalveolar lavage (BAL) at the lingula, which showed the presence of eosinophilia greater than 40%. As a consequence, we treated the patient with high-dose corticosteroids that completely resolved the respiratory symptoms. This case report highlights the difficulty of making alternative diagnoses during the COVID-19 pandemic, especially for rare lung diseases such as AEP, which may have initial characteristics similar to COVID-19.

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“…A typical radiologic feature of AEP is the localization in the upper lobes without basilar involvement of unilateral or bilateral opacities, typically with no segmental distribution. 11 …”

Section: Discussionmentioning

confidence: 99%

<p>May 2020: Is It Always COVID-19 No Matter What?</p>

Livrieri¹,

Ghidoni²,

Piro³

et al. 2020

IMCRJ

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show abstract

“…12 CT scan shows the nodules better and the typical pattern consists of widespread ill-defined centrilobular nodules and opacities scattered throughout the lung parenchyma bilaterally. 13,14 Table 3 shows the differential diagnosis of diffuse centrilobular nodules and opacities. The cases 1, 2 and 4 showed this typical picture on HRCT.…”

Section: Discussion Of Managementmentioning

confidence: 99%

Tropical Pulmonary Eosinophilia- An Elaborate Case Series

Utpat¹,

Sanghavi²,

Desai³

et al. 2019

jebmh

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“…Pulmonary eosinophilia is a rare condition but its diagnosis is challenging, because it can have the same diverse clinical and radiographic presentations seen in other common pulmonary conditions. Radiological manifestations show pulmonary infiltrates, characterized by foci of air-space consolidation and focal ground-glass opacities, can be seen in pulmonary eosinophilia of all causes ( 9 ). Clinicians should be alert to these syndromes and must think of them in any lung disease differential diagnoses.…”

Section: Discussionmentioning

confidence: 99%

Pulmonary Eosinophilic Inflammatory Infiltration Post-Intensive Care in a Nearly Drowned Young Man with Papillary Fibroelastoma: A Rare Complication Discovered by Forensic Autopsy

et al. 2018

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Papillary fibroelastoma is a rare benign lesion of heart (1). It is the second most common primary cardiac neoplasm, accounting for 4.4-8% of all tumors of the heart (2). We described a forensic autopsy of a nearly drowned young man with cardiac papillary fibroelastoma who died because of a pulmonary inflammatory infiltration rich in granulocytes after intensive care. This occurrence is rare but possible and should be kept in mind because a lung inflammatory infiltrate rich in eosinophilic granulocytes can be present in different pathological conditions and differential diagnoses are often difficult to do.

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Imaging of Eosinophilic Lung Diseases

Cited by 33 publications

References 92 publications

<p>May 2020: Is It Always COVID-19 No Matter What?</p>

<p>May 2020: Is It Always COVID-19 No Matter What?</p>

Tropical Pulmonary Eosinophilia- An Elaborate Case Series

Pulmonary Eosinophilic Inflammatory Infiltration Post-Intensive Care in a Nearly Drowned Young Man with Papillary Fibroelastoma: A Rare Complication Discovered by Forensic Autopsy

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