Abstract:<b><i>Background:</i></b> Tolvaptan was approved for the treatment of autosomal dominant polycystic kidney disease (ADPKD). However, the official indication of “rapidly progressive disease” is described differently in the clinical guidelines. We aim to define “rapidly progressive disease” by risk of ESRD, which is evaluated using estimated height-adjusted total kidney volume (HtTKV) growth rate. <b><i>Methods:</i></b> The risk of ESRD was retrospectively analyzed… Show more
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