volume 24, issue 3, P226-232 2009
DOI: 10.1590/s0102-86502009000300012
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Abstract: ABSTRACT Purpose:To evaluate the effects of iloprost a prostacyclin analogue on the hepatic IR injury in rats. Methods: Forty male SpragueDawley rats (250-300 g) were divided into four groups each containing 10 rats;-(1) controls: data from unmanipulated animals; (2) sham group: rats subjected to the surgical procedure, except for liver I/R, and given saline; (3) I/R group: rats that underwent liver ischemia for 45 min followed by reperfusion for 45 min; (4) I-R/ Iloprost group: rats pretreated with iloprost …

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