volume 295, issue 6590, P78-80 1987
DOI: 10.1136/bmj.295.6590.78
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A Fornasieri, R A Sinico, P Maldifassi, P Bernasconi, M Vegni, G D'Amico

Abstract: Circulating IgA-antigliadin antibodies were detected with enzyme linked immunosorbent assay (ELISA) in four of 121 patients (3%) who had IgA mesangial nephropathy and 14 of 17 children (82%) who had untreated coeliac disease. No positive cases were present in the 54 healthy subjects ofthe control group. Three patients who had IgA nephropathy and IgA-antigliadin antibodies underwent jejunal biopsy, and two showed mucosal atrophy. In these two patients urinary abnormalities, together with the IgA-antigliadin ant…

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