Idiopathic hypertrophic cranial pachymeningitis

Rojana-udomsart, Arada; Pulkes, Teeratorn; Viranuwatti, Kaseansom; Laothamatas, Jiraporn; Phudhichareonrat, Suchart; Witoonpanich, Rawiphan

doi:10.1016/j.jocn.2006.11.020

Cited by 34 publications

(32 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Direct compression, 1 spread of in‰ammation from adjacent thickened meninges, 2 and secondary ischemic damage of the optic nerve are the candidate mechanisms. 11 Our patient experienced unilateral visual dysfunction despite bilateral dilated SAS of the optic nerves. Interestingly, ophthalmic examination revealed central scotoma, a characteristic visual disturbance that suggested ischemic damage as the likely pathogenesis of optic nerve involvement.…”

Section: Discussionmentioning

confidence: 60%

Reversible Distension of the Subarachnoid Space around the Optic Nerves in a Case of Idiopathic Hypertrophic Pachymeningitis

et al. 2012

View full text Add to dashboard Cite

Idiopathic hypertrophic pachymeningitis (IHP) is a chronic in‰ammatory disease of unknown cause. We report a case of IHP with bilateral distended subarachnoid space (SAS) of the optic nerves and unilateral visual disturbance. We observed marked amelioration of magnetic resonance (MR) imagingˆndings after initiation of treatment with prednisolone. This radiologicalˆnding implicates optic nerve sheath involvement that aŠects cerebrospinal ‰uid (CSF) dynamics around the optic nerve.

show abstract

Section: Discussionmentioning

confidence: 60%

Reversible Distension of the Subarachnoid Space around the Optic Nerves in a Case of Idiopathic Hypertrophic Pachymeningitis

et al. 2012

View full text Add to dashboard Cite

show abstract

“…The majority of cases are the diffuse linear type, which causes various symptoms due to fibrous entrapment of cranial nerves or ischemia; symptoms include 1) headache with or without increased intracranial pressure, and 2) cranial neuropathy. 6,7,14,24 Immunosuppressants such as steroids, azathioprine, and methotrexate are considered the main treatment options, and are usually effective. 1,10,25 The disease course is highly variable, but it usually shows a chronic relapsing and remitting course.…”

Section: Discussionmentioning

confidence: 99%

“…1,10,25 The disease course is highly variable, but it usually shows a chronic relapsing and remitting course. 15,24 On the con- trary, a nodular type is not common and resembles a neoplasm, which could lead to surgical removal.…”

Section: Discussionmentioning

confidence: 99%

Immunoglobulin G4–related hypertrophic pachymeningitis involving cerebral parenchyma

Kim¹,

Kim

Cho³

et al. 2011

JNS

View full text Add to dashboard Cite

The authors report a case of IgG4-related hypertrophic pachymeningitis that involved cerebral parenchyma. The mass was removed surgically. Histopathological studies showed diffuse infiltration of lymphoplasmacytic cells without evidence of Langerhans histiocytes or meningothelial cells. Immunoglobulin G4 was strongly positive on immunohistochemical staining. The Gd-enhanced lesion deep inside brain parenchyma was completely resolved after 3 months of oral corticosteroid medication. A nodular type of hypertrophic pachymeningitis that mimics a meningioma is rare. Nevertheless, preoperative presumption is very important, and immunohistochemical studies for IgG4 may be helpful in the differential diagnosis.

show abstract

“…Meningitis with the disturbance of ocular movement has been reported in mycotic meningitis (8), tuberculous meningitis (9), carcinomatous meningitis (10), and pachymeningitis (11). The causes of oculomotor nerve palsy in these meningitides were neuritis, angiitis, invasion of carcinoma, and direct expansion of inflammation, respectively.…”

Section: Discussionmentioning

confidence: 99%

Purulent Meningitis Caused by Actinomyces Successfully Treated with Rifampicin: A Case Report

et al. 2011

View full text Add to dashboard Cite

A 64-year-old woman presented with fever and headache. Lumbar puncture revealed cerebrospinal fluid (CSF) that contained 67,386/mm 3 of WBC; CSF culture revealed Actinomyces species. She was diagnosed with purulent meningitis caused by actinomyces, and treated with intravenous ampicillin 12 g/day. The administration of ampicillin was effective, but not sufficient to control the inflammation in CSF. CSF inflammation persisted and a gradual increase in granulation tissue was found in the subdural space on lumbar MRI. After administration of rifampicin 450 mg/day, the CSF was normalized and the enhancement of granulation tissue decreased. The patient completely recovered 5 months after the therapy was initiated. We suggest that rifampicin may be an option for the treatment of meningitis caused by actinomyces.

show abstract

Idiopathic hypertrophic cranial pachymeningitis

Cited by 34 publications

References 11 publications

Reversible Distension of the Subarachnoid Space around the Optic Nerves in a Case of Idiopathic Hypertrophic Pachymeningitis

Reversible Distension of the Subarachnoid Space around the Optic Nerves in a Case of Idiopathic Hypertrophic Pachymeningitis

Immunoglobulin G4–related hypertrophic pachymeningitis involving cerebral parenchyma

Purulent Meningitis Caused by Actinomyces Successfully Treated with Rifampicin: A Case Report

Contact Info

Product

Resources

About