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Cited by 26 publications
(5 citation statements)
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“…However, the eleven patients here showed increasing reticulocytosis with an increase in the Hb concentration while on oxymetholone. A previous review of our patients before the advent of oxymetholone showed only a 25 % remission rate (Israel and Wilkinson, 1961), and it would appear that oxymetholone has significantly improved the survival rate.…”
Section: Discussionmentioning
confidence: 65%
“…However, the eleven patients here showed increasing reticulocytosis with an increase in the Hb concentration while on oxymetholone. A previous review of our patients before the advent of oxymetholone showed only a 25 % remission rate (Israel and Wilkinson, 1961), and it would appear that oxymetholone has significantly improved the survival rate.…”
Section: Discussionmentioning
confidence: 65%
“…Acute leukaemia arising in patients thought to be suffering from aplastic anaemia has been reported on several occasions (Adams et al, 1951;Block et al 1953;Mohler and Leavell, 1958;Wetherley-Mein, 1960), but it is a rare occurrence, and in the 102 cases of aplastic anaemia reported by Bernard and Najean (1965), the 60 reported by Lewis (1965), and the 45 reported by Israels and Wilkinson (1961) none developed leukaemia. During the past 10 years only five such patients have been seen in the department of clinical haematology at Manchester Royal infirmary and four of these occurred in the past 18 months following the treatment of the original aplastic anaemia with oxymetholone.…”
Section: Introductionmentioning
confidence: 99%
“…In the light of these considerations it is impossible to assess the true rate of spontaneous remission at all accurately. The interested reader must perforce read in detail the reviews of Boon and Walton (1951), Heaton, Crosby, and Cohen (1957), Scott et al (1959), andlsraels andWilkinson (1961). It is not unlikely, however, that somewhat less than one-third of such cases as are commonly labelled aplastic anaemia may recover spontaneously.…”
Section: Discussionmentioning
confidence: 99%