Identifying patterns behind the changes in skin pores using 3‐dimensional measurements and K‐means clustering

Lee, SeongWoo; Cherel, Marie; Gougeon, Sarah; Jeong, Eui Taek; Lim, Jun Man; Park, Sun Gyoo

doi:10.1111/srt.13082

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…Aging and its associated collagen modifications reduce tissue remodeling by matrix metalloproteinases and decrease the structural and mechanical integrity of collagen fibers 28 . It was assumed that pores would be more noticeable with older age as they become larger and deeper 8,29 . With age, collagen breaks down, causing skin to lose its elasticity.…”

Section: Discussionmentioning

confidence: 99%

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Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study

Salem

Salah²,

Ibrahim

2023

J of Cosmetic Dermatology

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Enlarged facial pores are common cosmetic concerns that are attributed to multiple factors. Excess sebum production, decreased skin elasticity, and increased hair follicle volume are the three main causes of enlarged pores. Other factors include sex, aging, excessive sun exposure and improper use of cosmetic products. 1 Due to great psychological impact, people have been trying to find treatment for this problem. Many treatment options are available including isotretinoin, chemical peeling, and laser therapy. 2Microbotox has been proved to be effective in improving the sheen and texture of the skin, as well as decreasing sweat and sebum production and enlarged pores as it causes atrophy of sebaceous glands, which subsequently causes tightening of the skin envelope. 3 Microneedles (MNs) can create hundreds of reversible microchannels in non-invasive manner to enhance transdermal drug delivery and promote collagen production. 4 Depending on the previously mentioned data, this study aimed to compare the efficacy and longevity of intradermal microbotox

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Section: Discussionmentioning

confidence: 99%

“…28 It was assumed that pores would be more noticeable with older age as they become larger and deeper. 8,29 With age, collagen breaks down, causing skin to lose its elasticity. As the skin relaxes, pores dilate and get more visible.…”

Section: Discussionmentioning

confidence: 99%

Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study

Salem

Salah²,

Ibrahim

2023

J of Cosmetic Dermatology

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“…Principally, skin pores are openings (holes) of pilosebaceous follicles. The size of skin pores will increase along the increase of age, this is one of the characteristics of skin aging [20]. Reduction in pore size of skin applied to turmeric extract and tamarind cream for 28 days in Table 7, according to research by Iskandar et al [21].…”

Section: Pore Sizementioning

confidence: 99%

Assessing the effectiveness of turmeric and tamarind leaves extract cream as anti-aging in vivo

Harsojuwono¹,

Satriawan²,

Mulyani³

2023

Int. J. Biol. Pharm. Sci. Arch.

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Turmeric and tamarind leaves extract creams have potential as anti-aging agents, but their use has never been studied in vivo. Therefore the purpose of this study was to determine the effectiveness of turmeric and tamarind leaves extract cream in maintaining skin quality in vivo. This research was carried out by applying turmeric and tamarind leaf extract cream to 24 volunteers (having received approval from the ethical commission). Variables observed included sebum content, pore size, pigment content, moisture or moisture content, elasticity and collagenase content. The results showed that turmeric and tamarind leaves extract cream can increase sebum content up to 31.1%, reduce pore size to 0.017 mm, increase pigment content up to 13.2%, moisture up to 54.2%, elasticity up to 21.4% and collagenase content up to 37.3%.

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Facial pore refining by targeting dermal and epidermal functions: Assessment across age and gender

De Tollenaere,

Meunier,

Durduret

et al. 2024

J of Cosmetic Dermatology

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BackgroundConspicuous facial pores are benign but represent a cosmetic concern for men and women. Recent works described dermal and epidermal impairments as clinical causes of enlarged pores. Morphological modifications of skin at the site of pores were associated with collagen density loss, possible alteration of extracellular matrix and abnormal differentiation of keratinocytes.AimsA composition containing mannose‐6‐phosphate (Active Complex) was designed to address these different aspects of pore enlargement. In vitro and ex vivo evaluations were conducted in different models mimicking disturbance of dermal and epidermal functions. The pore refining activity of Active Complex was assessed in two clinical trials studying a Caucasian women cohort and an Asian men cohort.ResultsAt the dermal level, Active Complex upregulated collagen I and decorin synthesis, and genes encoding collagens I, III, V, VII, XVII; suggesting its ability to favor collagen fiber organization and anchorage. The downregulation of matrix metalloprotease, involved in extracellular matrix degradation, reinforced the protective effect of Active Complex in the dermis. Active Complex down modulated differentiation markers in keratinocytes as well as genes involved in cell renewal. Study of reconstructed human epidermis modeling keratinocyte hyperproliferation revealed that Active Complex mitigated two markers of this state: number of nuclei in the stratum corneum and involucrin expression. Clinical trials confirmed the pore refining activity of Active Complex on men and women of different ages and ethnicities; −24% total skin pore area after 56 days of application on women, and −30.2% on men after 7 days.ConclusionsThis work demonstrates the interest to target dermal and epidermal modifications described in conspicuous pore area, especially dermis fiber organization, to address this cosmetic concern.

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Identifying patterns behind the changes in skin pores using 3‐dimensional measurements and K‐means clustering

Cited by 6 publications

References 15 publications

Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study

Microbotox injection versus its topical application following microneedling in the treatment of wide facial pores: A split face comparative study

Assessing the effectiveness of turmeric and tamarind leaves extract cream as anti-aging in vivo

Facial pore refining by targeting dermal and epidermal functions: Assessment across age and gender

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