Identification of the Therapeutic Effects of Gamma-Irradiated Chamomile Aqueous Extract Against Alcohol Induced Hepato-nephrotoxicity in Rats

el-Megid, Mohamed H.M. Abd; Azeem, Amir; EL-Shahat, Amro Nagah; Mekawey, H. M. S.

doi:10.21608/ejrsa.2017.4467

Cited by 4 publications

(1 citation statement)

References 15 publications

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“…Groups of chamomile in table (2) showed improvement in ALT, AST, and ALP serum after the period of the experiment comparison with groups without chamomile and this improvement maybe due to the components of chamomile according to Satyal et al, (2015) and who obtained that chamomile flowers aqueous extract (CFME) and fennel seeds aqueous extract (FSME) on azathioprine (AZA) have hepatoprotective potentials against AZA probably due to their antioxidant properties and radical scavenging activity. Also, these results agreed with the hypothesis that chamomile (Matricaria recutita L.) extent therapeutic effects by antioxidant and free radical scavenging actions (Abd El-Megid et al, 2017). Effect of chamomile as 5% on (MSG), (E110) and (SDBB), on the kidney function in male albino rats: Data in Table (3) revealed the mean value of (Urea) (mg/dl) of rats fed on various diets.…”

Section: Group Of Ratssupporting

confidence: 85%

Amerolative Influence of Chamomile (Matricaria recutita L.) on Synthetic Food Additive Induced Probable Toxicity in Male Albino Rats التأثير المخفف للبابونج علي السمية المحتملة للمضافات الغذائية الصناعية في ذکور الجرذان البيضاء

salah-eldin

Abd-Allah

2021

Journal of Food and Dairy Sciences

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Monosodium glutamate (MSG), various organic synthetic colourants such as Sunset yellow (E110), and synthetic dye brilliant blue colouring are among the over 25,000 substances used to preserve, colour, or improve meals. Many food additives have the potential to have detrimental health effects, which makes us question about their safety. The possible adverse health effects of different food additives prompt us to doubt the safety of its widespread use. Therefore, in this study, we will use chamomile as a natural product to reduce the negative effects of these food additives. 45 male albino rats weighing 150-180 g b.wt. each, and divided into 9 equal groups, first was kept as a control-ve group, while group 2,3,4,5 were control+ve given Monosodium glutamate (MSG) from the basal diet (70 mg/kg), Sunset yellow (E110) 2mg/kg b. wt. dissolved in distilled water, and synthetic dye brilliant blue (SDBB) 2mg/kg b.wt. then give the fifth group (MSG-E110-SDBB) dissolved in distilled water daily for 56 days. The other groups (6-7-8-9) were given MSG, E110, DBB, as well as tested chamomile. Chamomile (Matricaria recutita L.) is included in the baseline diet at a rate of 5%. The effects on liver function, kidney function, Malondialdehyde (MDA), Superoxide dismutase activity (SOD), catalase (CAT), and reduced glutathione GSH, as well as histological abnormalities in the liver and brain, were then investigated. The results found that feeding with chamomile improved liver function and kidney function and other biological parameters that are after consuming food additives frequently.

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Section: Group Of Ratssupporting

confidence: 85%

Amerolative Influence of Chamomile (Matricaria recutita L.) on Synthetic Food Additive Induced Probable Toxicity in Male Albino Rats التأثير المخفف للبابونج علي السمية المحتملة للمضافات الغذائية الصناعية في ذکور الجرذان البيضاء

salah-eldin

Abd-Allah

2021

Journal of Food and Dairy Sciences

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Thymol Reduces Hepatorenal Oxidative Stress, Inflammation and Caspase-3#xd; Activation in Rats Exposed to Indomethacin

Stephanie

David

Farombi

2022

Egyptian Journal of Basic and Applied Sciences

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Biochemical characterization of spiromesifen and spirotetramat as lipid synthesis inhibitors on cotton leaf worm, Spodoptera littoralis

et al. 2019

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Background: Two lipid synthesis inhibitors compounds (spiromesifen SPM and spirotetramat SPT) were used against the second instar larvae of cotton leaf worm, Spodoptera littoralis under laboratory condition. Toxicity of both compounds was tested. Effect of these insecticides on total lipid also was determined. Results: The obtained results showed that both compounds were moderately toxic against the second instar larvae of S. littoralis. The mortality percentages caused by the field rate of spiromesifen and spirotetramat were 51.7 and 60.0%, respectively. The lethal concentrations for 50% of tested insect population (LC 50) were 170.1 and 42.2 ppm, respectively. The total lipid content was determined in treated larvae and compared with the untreated. The percentage of total lipid in spiromesifen-and spirotetramat-treated larvae was 2.17 and 2.21%, respectively, compared with 2.42% in untreated larvae. GC/MS also was used in identification of fatty acids composition of S. littoralis larvae. Conclusion: The results cleared that 13 fatty acids were identified in S. littoralis larvae. The obtained results showed significant difference in percentages of fatty acids with both treated and untreated larvae and also, between tested compounds. Some fatty acids were existed in untreated larvae but not existed in treated larvae.

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Identification of the Therapeutic Effects of Gamma-Irradiated Chamomile Aqueous Extract Against Alcohol Induced Hepato-nephrotoxicity in Rats

Cited by 4 publications

References 15 publications

Thymol Reduces Hepatorenal Oxidative Stress, Inflammation and Caspase-3#xd; Activation in Rats Exposed to Indomethacin

Biochemical characterization of spiromesifen and spirotetramat as lipid synthesis inhibitors on cotton leaf worm, Spodoptera littoralis

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