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Cited by 14 publications
(21 citation statements)
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References 43 publications
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“…Many researchers have investigated various dietary supplements to inhibit muscle pathology or strengthen non-diseased muscles, whether it be for athletes or against aging, type 2 diabetes, or MD [ 83 , 84 , 85 , 86 , 87 , 110 , 128 , 129 , 130 , 131 , 132 , 133 ]. In MD, increasing the percentage of slow fibers is often the goal, but not necessarily the only goal.…”
Section: Dietary Supplementsmentioning
confidence: 99%
See 1 more Smart Citation
“…Many researchers have investigated various dietary supplements to inhibit muscle pathology or strengthen non-diseased muscles, whether it be for athletes or against aging, type 2 diabetes, or MD [ 83 , 84 , 85 , 86 , 87 , 110 , 128 , 129 , 130 , 131 , 132 , 133 ]. In MD, increasing the percentage of slow fibers is often the goal, but not necessarily the only goal.…”
Section: Dietary Supplementsmentioning
confidence: 99%
“…The benefits include reduced ROS, increased grip strength, decreased fibrosis, and improved echo parameters. These benefits can be direct or as a result of decreased inflammation [ 132 ] and a shift from M1 to M2 macrophages [ 133 ]. These results were so promising that clinical trials were initiated.…”
Section: Fatty Acid Supplementsmentioning
confidence: 99%
“…The beneficial effect of intramuscular MSC delivery of lowering the creatine kinase level has recently been reported in a study on the intramuscular transplantation of placenta-derived MSCs in mdx mouse [35]. Another study on the experimental mdx mouse model has also confirmed that the creatine kinase level and plasma cytokine levels, especially with respect to TNFα, INFγ, IL-6, and TGFβ, were useful biomarkers for the assessment of the disease progression and the response to cellular therapy [36].…”
Section: Discussionmentioning
confidence: 76%
“…Delivering taurine, an amino acid that is abundant in milk, to juvenile preweaned mdx mice prevented the acute onset of myonecrosis at 22 days and decreased the TNF levels, neutrophil content and MPO activity typically seen in untreated mdx muscles upon weaning (Terrill et al, 2016c). Furthermore, co-administration of deflazacort, an anti-inflammatory and immunosuppressant glucocorticoid commonly used to treat DMD patients, and omega-3 fatty acids to mdx mice resulted in reduced levels of serum TNF (de Carvalho et al, 2018). Taken together, these studies indicate that changes in blood TNF levels are reflecting the changes in tissue pathology and treatment responsiveness, supporting the notion that blood TNF is a potentially useful clinical biomarker.…”
Section: Resident Mast Cells In Dystrophic Musclementioning
confidence: 98%