volume 1, issue 1, P20-27 2010
DOI: 10.5155/eurjchem.1.1.20-27.11
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Abstract: KEYWORDSThis paper describes the separation, identification and proposed structures of the degradation products formed during degradation analysis of aripiprazole in its final dosage form by high performance liquid chromatography (HPLC) coupled with quadrupole time-offlight mass spectrometry (QToF-MS). The drug product was subjected to stress conditions including acid, base, thermal, oxidation, humidity and photolytic degradations. Aripiprazole was found to be stable in all conditions except in thermal and pe…

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