Search citation statements

Order By: Relevance

Paper Sections

Select...
3

Citation Types

0
4
0

Year Published

1991
1991
2005
2005

Publication Types

Select...
3

Relationship

0
3

Authors

Journals

citations
Cited by 14 publications
(4 citation statements)
references
References 26 publications
0
4
0
Order By: Relevance
“…Since even in steady-state the 2R.Pgp/-cells accumulated less doxorubicin (Table I) or vincristine (Kuiper et al, 1990), an active extrusion process could be present. Active drug extrusion processes for different types of drugs, not related to Pgp overexpression, have in fact been reported recently (Henderson & Tsuji, 1990;Hindenburg et al, 1989;McGrath et al, 1989a,b). In such highly resistant cells anthracycline resistance could also be related to differences in drug binding to nuclear and cytoplasmic bindings sites (Hindenburg et al, 1989).…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Since even in steady-state the 2R.Pgp/-cells accumulated less doxorubicin (Table I) or vincristine (Kuiper et al, 1990), an active extrusion process could be present. Active drug extrusion processes for different types of drugs, not related to Pgp overexpression, have in fact been reported recently (Henderson & Tsuji, 1990;Hindenburg et al, 1989;McGrath et al, 1989a,b). In such highly resistant cells anthracycline resistance could also be related to differences in drug binding to nuclear and cytoplasmic bindings sites (Hindenburg et al, 1989).…”
Section: Resultsmentioning
confidence: 99%
“…Active drug extrusion processes for different types of drugs, not related to Pgp overexpression, have in fact been reported recently (Henderson & Tsuji, 1990;Hindenburg et al, 1989;McGrath et al, 1989a,b). In such highly resistant cells anthracycline resistance could also be related to differences in drug binding to nuclear and cytoplasmic bindings sites (Hindenburg et al, 1989). Since different independently selected, lowly resistant isolates from SW-1573 cells showed the Pgp/-multidrug resistance , which now has been shown to be related to decreased doxorubicin N/C ratio's, a mutation in one gene product could be responsible for the observed resistance pattern in Pgp/-cells.…”
Section: Resultsmentioning
confidence: 99%
“…The specificity of the transporter is clearly shown by the relatively small transport effect of the in~ racellularly formed GS-SG complex (obtained in millimolar le"els during GSH depletion by diamide), or the selective inhi!~ition of the MRP-dependent calcein movements by PGA1, al~d not by several other closely related prostaglandins. An earlier report [29], by studying multidrug resistance in L1210 m,)use leukaemia cell line, demonstrated a pattern of shared st, bstrates and inhibitors closely resembling that shown in the plesent paper (including verapamil, quinidine, cholate, and pJ ostaglandin A1).…”
Section: Resultsmentioning
confidence: 99%
“…Studies with mouse L1210 cells have identified multiple ATP-dependent export pumps for methotrexate (MTX), sharing urate as a substrate (12). Furthermore, in human erythrocytes an ATP-dependent urate transporter has been described (22).…”
mentioning
confidence: 99%