2016
DOI: 10.1007/s00705-016-3145-8
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Abstract: The classical swine fever (CSF) is a highly contagious viral disease of pigs and wild boar. The CSF causes great economic losses for pork production and the occurrence of the disease is notifiable to the OIE. The objective of this work was to identify and characterize CSF virus isolates from Brazil. Seven viral isolates were obtained and the full-length E2 sequences were analyzed. Phylogenetic analysis revealed a different segregation pattern between Brazilian isolates and members of subgenotype 1.1, forming a… Show more

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Cited by 14 publications
(12 citation statements)
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“…In fact, genetic information regarding CSFV genotype 3 has been not reported since the report of a Korean strain in 1999 [Correction added after initial online publication on 10 January 2018: The year '1988' was changed to '1999'.] and reports of disease outbreaks by CSFV genotype 1 have been limited to Central and South America (Postel et al., ; Silva et al., ). One suggested reason for a global switch in predominant viral genotype is that all CSFV vaccine strains target genotype 1 (Chen et al., ).…”
Section: Introductionmentioning
confidence: 99%
“…In fact, genetic information regarding CSFV genotype 3 has been not reported since the report of a Korean strain in 1999 [Correction added after initial online publication on 10 January 2018: The year '1988' was changed to '1999'.] and reports of disease outbreaks by CSFV genotype 1 have been limited to Central and South America (Postel et al., ; Silva et al., ). One suggested reason for a global switch in predominant viral genotype is that all CSFV vaccine strains target genotype 1 (Chen et al., ).…”
Section: Introductionmentioning
confidence: 99%
“…In addition, at the time that the study reported by Rios et al. () was under revision, two new subgenotypes (1.5 and 1.6) from CSFV isolates that circulated in Brazil were reported (Silva et al., ). This last finding is indicative that the genetic diversity of CSFV could be broader than it was previously reported (Postel et al., ; Rios et al., ).…”
Section: Introductionmentioning
confidence: 99%
“…Our analyses indicate that it is not likely that subgenotype 1.4 descends from North American strains as its MRCA with subgenotype 1.1 lies decades before the first‐reported CSF outbreak in the US. Subgenotypes 1.5 and 1.6 have been described recently in South America (Silva et al., ), but they may have evolved from viruses present in the region since the nineteenth century.…”
Section: Discussionmentioning
confidence: 99%
“…The latest outbreaks in Ecuador seem to be a result of an introduction of the virus from Peru where closely related strains were reported in 2010 (Arainga et al., ). The Peruvian strains were reported as belonging to subgenotype 1.1 (Arainga et al., ), but the later description of novel subgenotypes from Brazil (Silva et al., ) places both, Peruvian and Ecuadorian strains, within subgenotype 1.6. The Brazilian strain from subgenotype 1.6 was obtained in Macapá that is located on the east coast of the country, indicating that strains from this subgenotype may be spread through the equatorial region of South America but have gone unnoticed due to limited sampling.…”
Section: Discussionmentioning
confidence: 99%
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