volume 66, issue 9, P5472-5478 1992
DOI: 10.1128/jvi.66.9.5472-5478.1992
View full text
E O Freed, D J Myers

Abstract: The envelope glycoprotein of the human immunodeficiency virus type 2 (HIV-2) is synthesized as a polyprotein precursor which is proteolytically processed to produce the mature surface and transmembrane envelope glycoproteins. The processed envelope glycoprotein species are responsible for the fusion between the viral envelope and the host cell membrane during the infection process. The envelope glycoprotein also induces syncytium formation between envelope-expressing cells and receptor-bearing cells. To charac…

expand abstract