Identificação do papilomavírus humano por biologia molecular em mulheres assintomáticas

Nonnenmacher, Bernadete; Breitenbach, Vanessa; Villa, Luisa L.; Prolla, João Carlos; Bozzetti, Mary Clarisse

doi:10.1590/s0034-89102002000100015

Cited by 44 publications

(40 citation statements)

References 20 publications

(24 reference statements)

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“…This result is, therefore, amongst the highest HPV prevalence values observed in Brazil to date and likely reflects the use of nested-PCR assays for data gathering, a method that has a higher analytical sensitivity compared with other HPV DNA detection strategies (Lipmann et al, 2010;Coser et al, 2011). Our HPV prevalence finding was also slightly higher than those previously found in populations within in the State of Rio Grande do Sul by PCR and hybrid capture analysis (Nonnenmacher et al, 2002;Rosa et al, 2008).…”

Section: Discussionsupporting

confidence: 49%

“…The worldwide prevalence in women with normal cytology is approximately 10% (de Sanjosé et al, 2007), whereas in women with abnormal cytology it is approximately 35% (Molijn et al, 2005). Studies conducted in several cities and states revealed a prevalence of HPV infection between 24.8 and 35.0% in Brazil (Nonnenmacher et al, 2002;Fernandes et al, 2008;Krambeck et al, 2008;Lippmann et al, 2010;Oliveira et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil

Coser¹,

T²,

Simon³

et al. 2013

Genet. Mol. Res.

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ABSTRACT. Human papillomavirus (HPV) infection is a common viral sexually transmitted infection and the main cause of cervical cancer in women worldwide. Epidemiological data on the prevalence of HPV in a given population is essential for the establishment of effective prevention strategies. The aim of this study was to determine HPV prevalence in women who attended a public health service within an urban center in Brazil. Cervical samples were collected from 337 women recruited from a primary public health care clinic in the city of Cruz Alta located in Rio Grande do Sul, the were detected in 83 (72.8%) and 48 (42.1%) samples, respectively. Furthermore, a great diversity of HPV genotypes was observed (18 high-risk, 12 low-risk, and 1 indeterminate). The most commonly identified low-risk types were candHPV62 (7.9%) and 61 (5.3%), while the most common high-risk types were 16 and 33 (8.8% each). Abnormal cytology was observed in 10 (3.0%) women, 9 of which were infected with HPV. Of the remaining 327 women with normal cytology results, 107 (32.7%) were positive for HPV DNA. HPV infection was correlated with younger age (less than 40 years), a first Pap smear, and other vaginal infections.

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Section: Discussionsupporting

confidence: 49%

Section: Introductionmentioning

confidence: 99%

Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil

Coser¹,

T²,

Simon³

et al. 2013

Genet. Mol. Res.

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“…The prevalence rate found in this study was similar to that reported in the same region (19.5%) by Lorenzato et al (28) in Recife, and higher compared to the prevalence rate observed in other regions of southeastern (17.0%) (23) and southern Brazil (16.0%) (29), in which PCR-based assays using the consensus primer MY09/11 were also used for the detection of viral DNA.…”

Section: Health Statussupporting

confidence: 89%

Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal, Brazil

et al. 2011

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Abstract. This study analyzed the prevalence of human papillomavirus (HPV) in cervical specimens obtained from women with normal cytology and with cervical cancer, in order to evaluate their correlation with health status and demographic characteristics, as well as sexual and reproductive activity in women treated at a cancer reference hospital in Natal, Northeast Brazil. A total of 158 women were divided into 2 groups according to their health status: group I comprised 110 women with normal cytology, and group II comprised 48 women with cervical cancer. Cervical smears were analyzed by cytological or histopathological examination for the detection of cytological alterations, and by PCR for HPV DNA detection using MY09/11 primers, followed by HPV genotyping by dot blot hybridization. Results showed overall HPV prevalence to be 24.5% in group I, with 19.1% of patients having single infection and 5.4% double infection. The HPV prevalence in group II was 85.4%, with 79.2% of patients having single and 6.2% double infection. We identified 10 different HPV genotypes, most with high oncogenic potential. HPV 16 was the most prevalent genotype in the two studied groups, followed by HPV 58 and HPV 18. High-risk HPV genital infection, chronological age, ethnicity, early onset of sexual and reproductive activities, multiple sexual partners and smoking increased the risk for cervical cancer.

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“…It can lead to a variety of benign, premalignant and malignant lesions in the mucosa and cutaneous tissues 1 . Genital HPV infection is one of the most frequent sexually transmitted diseases 2,3 . In a high prevalence context, infectivity and diagnosis are made by examining the clinical, subclinical and asymptomatic lesions; the dissemination of HPV is universal among the sexually active population, where men are an important means for the proliferation of the virus [1][2][3][4] .…”

Section: Introductionmentioning

confidence: 99%

“…Genital HPV infection is one of the most frequent sexually transmitted diseases 2,3 . In a high prevalence context, infectivity and diagnosis are made by examining the clinical, subclinical and asymptomatic lesions; the dissemination of HPV is universal among the sexually active population, where men are an important means for the proliferation of the virus [1][2][3][4] . It is estimated that 15 to 40% of the world's population is contaminated with HPV 5,6 ; furthermore, more than 500,000 new cases occur worldwide every year.…”

Section: Introductionmentioning

confidence: 99%

Level of behavior and knowledge concerning human papillomavirus among university students of a nursing college

Cirilo

Barbosa

Zambrano

2010

Rev. Soc. Bras. Med. Trop.

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Introduction: Human pappilomavirus is one of the most common sexually transmitted diseases, and persistent HPV infection is considered the most important cause of cervical cancer. It is detected in more than 98% of this type of cancer. This study aimed to determine the level of knowledge concerning human papillomavirus among nursing college students of a private educational institution located in the City of Bauru, SP, and correlate their knowledge according to the course year. Methods: A descriptive study with a quantitative approach, performed with a questionnaire that permitted the quantification of data and opinions, thus guaranteeing the precision of the results without distortions in analysis or interpretation. The survey was applied to randomly selected 1 st , 2 nd , 3 rd , and 4 th -year nursing college students. Twenty students from each level were selected during August 2009, totaling 80 students of both genders. Results: Observation revealed that 4

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Identificação do papilomavírus humano por biologia molecular em mulheres assintomáticas

Cited by 44 publications

References 20 publications

Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil

Prevalence and genotypic diversity of cervical human papillomavirus infection among women from an urban center in Brazil

Human papillomavirus prevalence in women with normal cytology and with cervical cancer in Natal, Brazil

Level of behavior and knowledge concerning human papillomavirus among university students of a nursing college

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