2004
DOI: 10.1590/s1516-84842004000100011
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Identificação de variantes de hemoglobina em doadores de sangue

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Cited by 2 publications
(3 citation statements)
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“…This analysis using both electrophoretic and chromatographic procedures has shown a consistent picture of thalassemia in Brazil with the analysis of 41,235 blood samples. [5][6][7][8] methodologies that included electrophoretical procedures, cytological tests and HPLC. We found 15% of hemoglobinopathy carriers with high frequencies of alpha thalassemia and Hb S. Beta thalassemia was found in 1.96% of the samples tested.…”
Section: To Editormentioning
confidence: 99%
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“…This analysis using both electrophoretic and chromatographic procedures has shown a consistent picture of thalassemia in Brazil with the analysis of 41,235 blood samples. [5][6][7][8] methodologies that included electrophoretical procedures, cytological tests and HPLC. We found 15% of hemoglobinopathy carriers with high frequencies of alpha thalassemia and Hb S. Beta thalassemia was found in 1.96% of the samples tested.…”
Section: To Editormentioning
confidence: 99%
“…Many hemoglobin variants have been described in Brazil, and with the significant admixture, the existence of interactions among thalassemic forms and variants are frequent. 7,10 The most common beta thalassemia mutation, predominant in Mediterranean populations including the Italian, Spanish and Portuguese, is common in inhabitants from the state of São Paulo. Molecular studies in this population show the high frequency of Mediterranean mutants such as the CD39 mutation.…”
mentioning
confidence: 99%
“…Organização Mundial de Saúde estima que mais de 5% da população mundial seja portadora de algum tipo de hemoglobinopatia (1) . Estima-se o surgimento de 700 a 1.000 novos casos anuais de doença falciforme no Brasil e prevalência de mais de 2 milhões de portadores do gene HbS (2) .…”
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