“…These investigators also reported that six serotypes (6A, 6B, 9V, 14, 19F, 23F) account for >80% of penicillin-or macrolide-resistant S. pneumoniae, worldwide. 9 Moreover in the US, an increase in the isolation of antibiotic resistant 19A strains has been reported, a strain associated with increased incidence of IPD. 10 Effective immunization against S. pneumoniae is the most effective method to reduce the impact of pneumococcal infections, including those caused by antibiotic resistant strains.…”