<i>Pseudomonas aeruginosa: can studies in engineered cells tell us why is it such a problem in people with cystic fibrosis?</i> Focus on “Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of <i>Pseudomonas aeruginosa</i>”

Zeitlin, Pamela L.

doi:10.1152/ajpcell.00257.2009

Cited by 4 publications

(1 citation statement)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…33 Individuals with CF have a defect in the transmembrane conductance regulator (CFTR). 34,35 In normal individuals, infection with this bacteria stimulates the formation of lipid rafts that contain the CFTR thus allowing the organism to invade the respiratory epithelium and initiate inflammatory and apoptotic processes leading to shedding of bacteria-containing epithelial cells. 35–37 However, in CF patients these responses are absent and P. aeruginosa becomes established as a chronic infection.…”

Section: Bacteriamentioning

confidence: 99%

Recent Developments in the Interactions Between Caveolin and Pathogens

Machado

Rodríguez

Adesse

et al. 2012

Advances in Experimental Medicine and Biology

View full text Add to dashboard Cite

Section: Bacteriamentioning

confidence: 99%

Recent Developments in the Interactions Between Caveolin and Pathogens

Machado

Rodríguez

Adesse

et al. 2012

Advances in Experimental Medicine and Biology

View full text Add to dashboard Cite

Transient up- and down-regulation of expression of myosin light chain 2 and myostatin mRNA mark the changes from stratified hyperplasia to muscle fiber hypertrophy in larvae of gilthead sea bream (Sparus aurata L.)

et al. 2015

View full text Add to dashboard Cite

Hyperplasia and hypertrophy are the two mechanisms by which muscle develops and grows. We study these two mechanisms, during the early development of white muscle in Sparus aurata, by means of histology and the expression of structural and regulatory genes. A clear stage of stratified hyperplasia was identified early in the development of gilthead sea bream but ceased by 35 dph when hypertrophy took over. Mosaic recruitment of new white fibers began as soon as 60 dph. The genes mlc2a and mlc2b were expressed at various levels during the main phases of hyperplasia and hypertrophy. The genes myog and mlc2a were significantly upregulated during the intensive stratified formation of new fibers and their expression was significantly correlated. Expression of mstn1 and igf1 increased at 35 dph, appeared to regulate the hyperplasia-to-hypertrophy transition, and may have stimulated the expression of mlc2a, mlc2b and col1a1 at the onset of mosaic hyperplasia. The up-regulation of mstn1 at transitional phases in muscle development indicates a dual regulatory role of myostatin in fish larval muscle growth.

show abstract

Caveolin-1 in renal disease

Chand¹

2018

Scientific J Genet Gene Ther

View full text Add to dashboard Cite

Caveolin-1 is the essential structural formation for lipid raft formation. It has been ascribed to several disease processes in humans due to its ubiquitous distribution. Patients with chronic kidney disease suffer great morbidity and mortality where manipulation of caveolin-1 could lead to new potential therapeutic targets in this patient group. This review highlights caveolin-1 structure, signalling and provides examples of studies of caveolin-1 single nucleotide polymorphism in chronic kidney disease.

show abstract

Pseudomonas aeruginosa: can studies in engineered cells tell us why is it such a problem in people with cystic fibrosis? Focus on “Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa”

Cited by 4 publications

References 20 publications

Recent Developments in the Interactions Between Caveolin and Pathogens

Recent Developments in the Interactions Between Caveolin and Pathogens

Transient up- and down-regulation of expression of myosin light chain 2 and myostatin mRNA mark the changes from stratified hyperplasia to muscle fiber hypertrophy in larvae of gilthead sea bream (Sparus aurata L.)

Caveolin-1 in renal disease

Contact Info

Product

Resources

About