Phialophora gougerotii:An opportunistic fungus in a patient treated with steroids

Abstract

A 53 year old Negro male with rheumatoid arthritis received various steroid compounds intermittently for 9 years and continuously for 5 years. After an intramuscular injection in the right buttock, he developed subcutaneous abscesses and sinus tracts at the site of inoculation, incision and drainage were performed twice, 4 years later. After an exacerbation of the abscesses, microscopic examination of the purulent material revealed hyphal elements. Culture of this * Present address : Laboratory, South Carolina Board of Health, Columbia, South Carolina 29201. "~ Markle Scholar in Academic Medicine. 241 Med Mycol Downloaded from informahealthcare.com by Chulalongkorn University on 12/27/14 For personal use only.

A case of chromoblastomycosis with an unusual clinical manifestation caused by Phialophora verrucosa on an unexposed area: treatment with a combination of amphotericin B and 5-flucytosine

“…Phialides assume a flask shape, collarettes a black‐coloured cup shape, and conidia an ovoid shape 3,12 . Infection by Phialophora species appears to show a predilection for debilitated and immunocompromised patients 13–15 . However, our patient had normal immune function as shown by the results of the lymphocyte function test, CD4/CD8 counts and multicell‐mediated immunity test.…”