In situsilver nanoparticle coating of virions for quantification at single virus level

Abstract

In situ labelling and encapsulation of biological entities, such as of single viruses, may provide a versatile approach to modulate their functionality and facilitate their detection at single particle level....

Impact electrochemistry for biosensing: advances and future directions

“…Compared with PtNPs of the same size, the detection sensitivity may be significantly enhanced when using current (and in most cases, charge) output mode of AgNPs. The direct electrolysis of AgNPs has been commonly used for the detection of various analytes, including viruses, 77 bacteria, 78 and tumor protein markers. 79 The first study related to this detection principle was conducted by Compton et al in 2015, where E. coli was labeled with a certain amount of AgNPs through electrostatic interaction.…”

Living virus‐based nanohybrids for biomedical applications

“…Polyphenols, a kind of molecules composed of more than two ortho phenolic hydroxyls, display a strong affinity to proteins via hydrophobic interactions and hydrogen bonds (Wang, Zhang, et al, 2022). Additionally, potent connections between protein-structured viruses and polyphenols can be further strengthened by the inclusion of metal ions, due to the coordination of metal ions and phenol hydroxyl groups (Bognar et al, 2022). Moreover, metal-phenolic networks (MPNs) have attracted attention due to their easy synthesis, low toxicity, and high affinity for a variety of bio-interfaces (Zhang, Xie, et al, 2021).…”

Nanomaterials for virus sensing and tracking

“…Silver nanoparticles (AgNPs), just like AuNPs, are noble metal nanoparticles that are commonly employed for virus sensing. 79,165,239,[340][341][342][343][344][345] Analogous to AuNPs, the optical properties, color, and sensing behavior of AgNPs are dependent on particle dimensions due to LSPR. 170 However, AgNPs are more cost-effective as well as electroactive and have a higher extinction coefficient.…”