In‐Silico Selection of Wound‐Healing Plant Secondary Molecules and Their Pro‐Healing Activities on Experimental Models
Omar Casadiego,
Oscar Macias,
Laura García
et al.
Abstract:This study explored the potential of plant‐derived molecules (PDMs) as a medicinal treatment for skin wounds. To assess their healing properties, 34 potential drug molecules (PDMs) and ten therapeutic targets were subjected to molecular docking and dynamics analysis, with allantoin used as a standard compound. Although aristolochic acid had the most potent inhibitory effect, its toxicity made it unsuitable for testing on cells and mice. Therefore, β‐caryophyllene (BC) and caryophyllene oxide (BCoxide) were cho… Show more
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