Cyclospore cayetanensisin Anhui, China

Abstract

Cyclospore cayetanensis infection is present in Anhui, China and it was confirmed to be a new pathogen associated with children diarrhea, adults obstinate diarrhea and diarrhea in immunocompromised individuals. Among all the infected individuals, adult obstinate diarrhea patients and immunocompromised individuals are common. Feces examination of oocysts and serological examination of the specific antibody will be of much help in the diagnosis of Cyclospore cayetanensis infection.

Cyclospora cayetanensis

“…Attempts toinfect several animals with C. cayetanensis have been unsuccessful, suggesting host specificity (Eberhard et al, 2000). Although C. cayetanensis was reported to be propagated in albino mice (Sadaka et al, 2001) and guinea pigs (Wang et al, 2002) the findings could not be confirmed (Ortega et al, 2010). The parasite has been detected in shellfish (Negm, 2003;Aksoy et al, 2014).…”

“…The findings indicated an inverse relationship between socioeconomic status and infection and showed that cyclosporiasis, as well as other communicable infections, affects families living in substandard housing developments. In Haiti and China, higher rates of infection have been noted in areas, where deficient sanitary facilities and personal hygiene and soil frequently contaminated with feces were present (Lopez et al, 2003;Wang et al, 2002;Zhou et al, 2011). with low socioeconomic status rather than age alone.…”

“…In contrast, the risk factors and routes of spread for C. cayetanensis in developing areas remain poorly understood. Variables related to water, eating fresh food, contact with soil, agricultural occupations, lack of hand washing, and factors associated with low socioeconomic status have been linked to infection (Wang et al, 2002;Chacin-Bonilla et al, 2007, 2008aZhou et al, 2011;Tandukar et al, 2013). The biologic and epidemiologic features of C. cayetanensis that facilitate transmission might involve an interplay among different routes of spread but the relative contributions of the different modes of transmission to the overall burden of cyclosporiasis are hard to quantify.…”

Update on Cyclospora cayetanensis , a Food-Borne and Waterborne Parasite

“…The assays used oocysts produced in guinea pigs. This animal model and serological testing need to be reproduced and validated by other scientists (191). A Western blot assay has been developed and can identify acute-from convalescent-phase cyclosporiasis (Y. R. Ortega, unpublished data).…”

“…Nonetheless, it cannot yet be ruled out that animals may play a role in the dissemination of Cyclospora by contaminating water and food products. Two reports indicate that Cyclospora can be propagated in guinea pigs (191) and albino mice (162). These studies could not be reproduced, and further analyses are needed to determine the susceptibility of these animals to infection by Cyclospora and their suitability as hosts or reservoirs of C. cayetanensis.…”