Chlamydia Pneumoniae: Comparison with Findings ofMycoplasmaPneumoniaeandStreptococcusPneumoniaeat Thin-Section CT

Nambu, Atsushi; Saito, Akitoshi; Araki, Tsutomu; Ozawa, Katsura; Hiejima, Yoshimitsu; Akao, Masaki; Ohki, Zennosuke; Yamaguchi, Hiroshi

doi:10.1148/radiol.2381040088

Cited by 84 publications

(80 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…S. pneumoniae, Klebsiella pneumoniae, Mycoplasma pneumoniae and Chlamydia pneumoniae are also common pathogens involved in community-acquired or nosocomial pneumonia. The average age of patients with M. catarrhalis infection tended to be greater than that of patients with pneumonia caused by other pathogens such as S. pneumoniae, K. pneumoniae, M. pneumoniae or C. pneumoniae (60 years, 61.5 years, 47.3 years and 57.7 years, respectively) [32][33][34]. Among the 109 patients with pulmonary infection caused by M. catarrhalis alone, pulmonary emphysema (67.9%) was the most commonly associated condition, followed by smokers (43.1%), cardiovascular disease (40.4%), malignant disease (37.6%), alcoholism (22.9%) and diabetes mellitus (16.5%).…”

Section: Discussionmentioning

confidence: 88%

“…The abnormal findings were predominantly seen in the lower zone and in the peripheral lungs. Nambu et al [32] reported that the CT findings in 41 patients with S. pneumoniae pneumonia consisted mainly of consolidation, reticular opacity and centrilobular nodules (90%, 39% and 32%, respectively). Previously, we have reported chest CT findings in 198 patients with acute K. pneumoniae pneumonia alone [33], in 42 patients with M. pneumoniae pneumonia alone [34] and in 40 patients with C. pneumoniae pneumonia alone [34].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pulmonary thin-section CT findings in acuteMoraxella catarrhalispulmonary infection

Okada¹,

Ando²,

Nakayama³

et al. 2011

BJR

View full text Add to dashboard Cite

Objective: Moraxella catarrhalis is an important pathogen in the exacerbation of chronic obstructive pulmonary disease. The aim of this study was to assess the clinical and pulmonary thin-section CT findings in patients with acute M. catarrhalis pulmonary infection. Methods: Thin-section CT scans obtained between January 2004 and March 2009 from 292 patients with acute M. catarrhalis pulmonary infection were retrospectively evaluated. Clinical and pulmonary CT findings in the patients were assessed. Patients with concurrent infection including Streptococcus pneumoniae (n572), Haemophilus influenzae (n561) or multiple pathogens were excluded from this study. Results: The study group comprised 109 patients (66 male, 43 female; age range 28-102 years; mean age 74.9 years). Among the 109 patients, 34 had community-acquired and 75 had nosocomial infections. Underlying diseases included pulmonary emphysema (n574), cardiovascular disease (n544) or malignant disease (n541). Abnormal findings were seen on CT scans in all patients and included ground-glass opacity (n599), bronchial wall thickening (n585) and centrilobular nodules (n579). These abnormalities were predominantly seen in the peripheral lung parenchyma (n599). Pleural effusion was found in eight patients. No patients had mediastinal and/or hilar lymph node enlargement. Conclusions: M. catarrhalis pulmonary infection was observed in elderly patients, often in combination with pulmonary emphysema. CT manifestations of infection were mainly ground-glass opacity, bronchial wall thickening and centilobular nodules. Moraxella catarrhalis is a Gram-negative, aerobic, oxidase-positive diplococcus that was first described in 1896 [1]. The pathogen, also known as Micrococcus catarrhalis, Neisseria catarrhalis and Brahamella catarrhalis, is a clinically important pathogen and is a common cause of respiratory infections, particularly otitis media in children and lower respiratory tract infection in elderly patients [2][3][4][5]. M. catarrhalis is considered to be the third most common and most important cause of bronchopulmonary infections after Streptococcus pneumoniae and Haemophilus influenzae [6,7]. In the Alexander project in Europe and the US between 1992 and 1993, M. catarrhalis was identified in 13.5% of bacterial isolates [8].M. catarrhalis has also gained attention as a nosocomial respiratory pathogen and as a community-acquired pathogen. On the basis of epidemiological evidence, the spread of M. catarrhalis was suggested to occur within the hospital environment [9,10]. McLeod et al [11] reported that 43 of 81 patients (53%) with M. catarrhalis infection were infected in a hospital and that the infection was associated with the proximity of the patient to other patients. Most nosocomial infections with M. catarrhalis involve the respiratory tract and outbreaks have been reported in respiratory units and paediatric intensive care units [10,12].M. catarrhalis infection has received increasing attention because it is an important factor in the acute exacerbation of...

show abstract

Section: Discussionmentioning

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Pulmonary thin-section CT findings in acuteMoraxella catarrhalispulmonary infection

Okada¹,

Ando²,

Nakayama³

et al. 2011

BJR

View full text Add to dashboard Cite

show abstract

“…Furthermore, the presence of bilateral bronchial wall thickening or centrilobular nodules may be highly suggestive for M. pneumoniae pneumonia. Nambu et al reported that the difference in frequency of bronchovascular bundle thickening (bronchial wall thickening) and peribronchovascular or centrilobular nodules between M. pneumoniae and S. pneumoniae was statistically significant (p = 0.004) [15]. Air-space consolidation with or without centrilobular or peribronchovascular nodules were often seen in both pneumonias and were nonspecific.…”

Section: Discussionmentioning

confidence: 99%

“…However, using this system there are still many cases where the guidelines cannot differentiate between M. pneumoniae pneumonia and S. pneumoniae pneumonia, and the JRS guidelines are seeking new specific parameters in order to improve this scoring system [4]. Some reports have focused on radiographic features using high-resolution computed tomography (HRCT) of M. pneumoniae pneumonia [11][12][13][14][15]. However, to our knowledge, there have been relatively few comparative studies that have investigated the radiographic findings of M. pneumoniae pneumonia versus S. pneumoniae pneumonia.…”

Section: Introductionmentioning

confidence: 99%

Radiographic Features of Mycoplasma Pneumoniae Pneumonia: Differential Diagnosis and Performance Timing

Miyashita

Sugiu

Kawai

et al. 2009

Chest

View full text Add to dashboard Cite

“…Children's infectious ILD are mostly attributed to primary airway infections. The infections of viruses, mycoplasma, and chlamydia first spread along the trachea and then pass through small and medium-sized bronchi, forming axial interstitial inflammation (Nambu et al, 2006). Airway mucosa and submucosa involvement caused by repeated infection is the main reason for the abnormal changes of bronchovascular bundles.…”

Section: Bronchovascular Bundle Abnormalitiesmentioning

confidence: 99%

High resolution computed tomography and classification of children with interstitial lung diseases

Lai

Cao

et al. 2014

Genet. Mol. Res.

View full text Add to dashboard Cite

ABSTRACT. High resolution computed tomography (HRCT) was used to classify children with interstitial lung diseases (ILD). Sixty children with ILD underwent HRCT in supine position under freerespiratory conditions during scanning. Children under 5 years old were sedated with chloral hydrate and the scanning scope was from the lung apex to the diaphragm. In children older than 5 years old, scans were obtained at three levels: aortic arch, tracheal carina, and 1 cm above the right diaphragm. Five infectious patients were followed up. Two experienced radiologists read the films blindly to observe the type and distribution of ground-glass opacities and bronchovascular bundle abnormalities. Bronchovascular bundles were thick in 49 patients, and were thick and stiff in 27 patients. Of the 41 infectious patients, 39 showed thickened bronchovascular bundles, and 26 showed thick and stiff bronchovascular bundles. Of the 19 non-infectious patients, bronchovascular bundles were thickened in 10 patients, and were thick and stiff in 1 patient. Fortyone patients showed lobular ground-glass opacity (32 infectious, 9 non-infectious). Twenty-seven patients showed both bronchovascular bundle abnormality and lobular ground-glass opacity (20 infectious, 7 non-infectious). Eighteen patients showed patchy or mosaic ground-glass opacity (16 infectious, 2 non-infectious). There were 4 cases of bronchiectasis. HRCT is the first non-invasive diagnostic method for children with ILD, and its different manifestations can be classified. In early manifestation, bronchovascular bundles were abnormal and complicated with lobular ground-glass opacity. Patchy ground-glass opacity was the most common manifestation, and appeared to be difficult to disappear. Bronchiectasis indicated that the disease is irretrievable.

show abstract

Chlamydia Pneumoniae: Comparison with Findings ofMycoplasmaPneumoniaeandStreptococcusPneumoniaeat Thin-Section CT

Abstract: C pneumoniae pneumonia demonstrates a wide spectrum of thin-section CT findings that are similar to those of S pneumoniae pneumonia and M pneumoniae pneumonia; airway dilatation and bronchovascular thickening were significantly more frequent in patients with C pneumoniae pneumonia.

Cited by 84 publications

References 15 publications

Pulmonary thin-section CT findings in acuteMoraxella catarrhalispulmonary infection

Pulmonary thin-section CT findings in acuteMoraxella catarrhalispulmonary infection

Radiographic Features of Mycoplasma Pneumoniae Pneumonia: Differential Diagnosis and Performance Timing

High resolution computed tomography and classification of children with interstitial lung diseases

Contact Info

Product

Resources

About