“…7,8 More recently, curcumin has been reported to inhibit HIV replication and was claimed for anti-HIV-1 and HIV-2 activities in a recent patent application. 9 Data showed that curcumin inhibited the replication of HIV-1 integrase protein for both the stand transfer and 3 0 -processing activities with IC 50 of 40 and 30 lM, respectively. [10][11][12] In addition, curcumin and related compounds have also been reported for inhibition of HIV-1 and HIV-2 proteases with IC 50 of 100 and 250 lM, respectively.…”