“…Subsequently, bHLH TFs and myogenic regulatory factors (MRFs), MyoD (Myod1) and Myf5, commit cells to a myogenic fate in a redundant fashion, whereas the MRFs myogenin and MRF4 (Myf6) control the differentiation of myoblasts into myofibers and myotubes (Bentzinger et al, 2012;Buckingham and Rigby, 2014). Likewise in plants, pre-specification of the shoot protodermal (L1) identity, which is controlled by the homeobox transcription factors MERISTEM LAYER 1 (ATML1) and HOMEODOMAIN GLABROUS 2 (HDG2), is required for the initiation of stomatal cell lineages (Takada et al, 2013;Peterson et al, 2013). The ectopic expression of ATML1 or HDG2 is sufficient to induce SPCH expression and subsequent stomatal differentiation in nonepidermal cells (Takada et al, 2013;Peterson et al, 2013).…”